K. Mechlem, T. Sellerer, M. Viermetz, J. Herzen, F. Pfeiffer
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We investigate the combination of two emerging X-ray imaging technologies, namely spectral imaging and differential phase contrast imaging. By acquiring spatially and temporally registered images with several different X-ray spectra, spectral imaging can exploit differences in the energy-dependent attenuation to generate material selective images. Differential phase contrast imaging uses an entirely different contrast generation mechanism: The phase shift that an X-ray wave exhibits when traversing an object. As both methods can determine the (projected) electron density, we propose a novel material decomposition algorithm that uses the spectral and the phase contrast information simultaneously. Numerical experiments show that the combination of these two imaging techniques benefits from the strengths of the individual methods while the weaknesses are mitigated: Quantitatively accurate basis material images are obtained and the noise level is strongly reduced, compared to conventional spectral X-ray imaging.
期刊介绍:
The IEEE Transactions on Medical Imaging (T-MI) is a journal that welcomes the submission of manuscripts focusing on various aspects of medical imaging. The journal encourages the exploration of body structure, morphology, and function through different imaging techniques, including ultrasound, X-rays, magnetic resonance, radionuclides, microwaves, and optical methods. It also promotes contributions related to cell and molecular imaging, as well as all forms of microscopy.
T-MI publishes original research papers that cover a wide range of topics, including but not limited to novel acquisition techniques, medical image processing and analysis, visualization and performance, pattern recognition, machine learning, and other related methods. The journal particularly encourages highly technical studies that offer new perspectives. By emphasizing the unification of medicine, biology, and imaging, T-MI seeks to bridge the gap between instrumentation, hardware, software, mathematics, physics, biology, and medicine by introducing new analysis methods.
While the journal welcomes strong application papers that describe novel methods, it directs papers that focus solely on important applications using medically adopted or well-established methods without significant innovation in methodology to other journals. T-MI is indexed in Pubmed® and Medline®, which are products of the United States National Library of Medicine.