确定姜黄凝胶作为洁治剂辅助治疗牙龈炎的疗效:一项随机对照试验

M. Devarathnamma, Anunay Pangarikar, Prachi Parab, Shivanand Aspalli, Nagappa Guttiganur, Janavathi Rangappa
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引用次数: 1

摘要

背景:牙龈炎是发生在口腔中最常见的牙周病之一,是由牙菌斑引起的,如果不治疗,可能发展为牙周炎。各种辅助化疗剂可用于斑块控制,有其自身的优缺点。因此,需要一种易于以低成本获得且没有任何副作用的斑块控制治疗剂。根据古代文献、阿育吠陀和印度传统文化,姜黄外用治疗皮肤和粘膜炎症。目的:评价莪术胶对牙龈健康的治疗作用及其在牙龈炎治疗中的可能应用。设置和设计:这项研究包括100名患有牙龈炎的参与者,他们被随机分为两组。受试者和方法:实验组-刮除并局部应用姜黄凝胶,对照组-单独刮除而不局部使用姜黄凝胶。在实验组和对照组的不同时间间隔(0、7、14和21天)评估临床参数(牙龈指数、牙龈出血指数和牙菌斑指数)。使用的统计分析:在组内,重复测量ANOVA模型用于一段时间内的重复观察,然后使用Dunnett检验进行多次比较。通过Student t检验比较实验组和对照组的正态分布数据。而对于偏斜的数据,则采用了Wilcoxon检验或Mann-Whitney U型检验。结果:与对照组相比,洁治后局部使用姜黄口服凝胶的组的牙龈健康参数有统计学意义的改善。结论:洁治后使用姜黄口服凝胶可显著改善牙龈炎的临床参数,无明显不良反应,这表明其可能在临床或社区层面的预防和治疗计划中用作局部辅助治疗。
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To determine therapeutic effect of curcuma gel on gingivitis as an adjunct to scaling: A randomized control trial
Context: Gingivitis is among the most prevalent periodontal disease occurring in the oral cavity, which is plaque induced and if untreated, can progress to periodontitis. Various adjunct chemotherapeutic agents are available for plaque control with their own pros and cons. Hence, a plaque-controlling therapeutic agent which is readily available at low cost and without any side effects is the need of the hour. According to the ancient texts, Ayurveda and the traditional culture of India, Curcuma longa is used externally for inflammation of skin and mucosa. Aims: To evaluate the therapeutic effect of curcuma gel on gingival health and its possible usage in the treatment of gingivitis. Settings and Design: This study comprises hundred participants with gingivitis which were divided randomly in two groups. Subjects and Methods: Experimental group – Scaling and topical application of curcuma gel and control group – Scaling alone without the topical application of curcuma gel. Clinical parameters (Gingival Index, Gingival Bleeding Index, and Plaque Index) were assessed at different time intervals (0, 7, 14, and 21 days) in both experimental and control groups. Statistical Analysis Used: Within groups, a repeated measures ANOVA model was used for repeated observations over a period which is followed by the Dunnett test for multiple comparisons. Experimental and control groups were compared for normally distributed data by Student's t-test. Whereas for skewed data, the Wilcoxon test or Mann–Whitney U-test was employed. Results: Statistically significant improvement of gingival health parameters was seen in the group which received topical curcuma oral gel application after scaling compared with the control group. Conclusions: Significant improvement in clinical parameters of gingivitis on the application of Curcuma oral gel after scaling with no obvious adverse effects suggesting its possible use as a topical adjunct treatment in clinical or community level prevention as well as treatment programs in the future.
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