食管切除术后导管旁裂孔疝的发生率、危险因素和处理

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2023-08-30 DOI:10.1093/dote/doad052.255
Rakesh Ahmed, J. Elliott, C. Donohoe, N. Ravi, J. Reynolds
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引用次数: 0

摘要

食管癌切除术后裂孔疝是食管癌手术中一种少见但严重的并发症。随着长期肿瘤预后的改善,食管切除术后裂孔疝在食管癌生存中越来越被认可。本研究的目的是评估管道旁裂孔疝(PHH)的发生率和危险因素,并描述三级转诊中心的管理方法。所有2008年至2022年因癌症接受食管癌切除术的患者均被纳入研究。早期PHH定义为发生在指数手术3个月内,所有其他PHH定义为晚期PHH。术后5年对所有无病患者进行计算机断层扫描监测。Kaplan Meier和Cox比例风险回归模型用于确定PHH的独立危险因素。研究了897例患者。早期PHH发生率为1.2%,晚期PHH发生率为5.7%。早期PHH无晚期复发。45.5%的早期和84.3%的晚期PHH是无症状的放射学发现。术后至PHH的中位时间为15.7个月。恶心、腹痛和呕吐是PHH最常见的症状。25.8%的病例需要手术治疗,早期PHH(63.6%)较晚期PHH (17.6%, P < 0.01)更为常见。手术入路(P < 0.001)、扩大脚或膈切除术(P < 0.001)和男性(P = 0.037)与裂孔疝的风险增加相关。摘要导管旁裂孔疝是肿瘤食管切除术后少见的并发症。对于术后前三个月出现PHH的患者,通常需要手术干预,但大多数无症状晚期PHH患者可能会得到预期的治疗。
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473. PARACONDUIT HIATUS HERNIA AFTER OESOPHAGECTOMY: INCIDENCE, RISK FACTORS AND MANAGEMENT
Hiatus hernia after oesophagectomy is an uncommon but serious complication of oesophageal cancer surgery. With improving long-term oncologic outcomes, post oesophagectomy hiatus hernia is an increasingly recognised entity in oesophageal cancer survivorship. The aim of this study was to assess the incidence of and risk factors for paraconduit hiatus hernia (PHH), and to describe management approaches in a tertiary referral centre. All patients undergoing oesophagectomy for cancer from 2008 to 2022 were included. Early PHH was defined as occurring within 3 months of index surgery, with all other PHH defined as late PHH. Surveillance computed tomography scans were undertaken among all disease-free patients to 5-years postoperatively. Kaplan Meier and Cox proportional hazards regression models were used to determine independent risk factors for PHH. 897 patients were studied. Early PHH occurred in 1.2%, and late PHH in 5.7% of patients. There was no late recurrence after early PHH. PHH was an asymptomatic radiologic finding in 45.5% of early and 84.3% of late cases. Median time to PHH was 15.7 months postoperatively. Nausea, abdominal pain and vomiting were the most common symptoms associated with PHH. Surgical intervention was required in 25.8% of cases, more commonly following early PHH (63.6%) as compared with late PHH (17.6%, P < 0.01). Operative approach (P < 0.001), extended resection of crura or diaphragm (P < 0.001) and male sex (P = 0.037) were associated with increased risk of hiatus hernia. Paraconduit hiatus hernia is an uncommon complication after oncologic oesophagectomy. Surgical intervention is often required for patients with PHH presenting in the first three months after surgery, but a majority of patients with asymptomatic late PHH may be managed expectantly.
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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