抗nmda脑炎:一种罕见的儿童脑炎1例报告

Saurav Khetan, N. Agrawal, Prakash Rajoli
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引用次数: 0

摘要

抗NMDA脑炎是儿童自身免疫性脑炎的第二常见病因;然而,当儿童出现脑炎相关症状时,它很难被诊断出来,通常也不被认为是一种差异。在儿童中,它主要表现为癫痫发作或无前驱症状的精神症状。在这里,我们介绍一个六岁的女孩,她出现了癫痫发作和不当行为。我们对她进行了病毒性脑炎的调查,如在我们地区非常常见的日本脑炎。然而,结果并不提示日本脑炎,进一步的研究随后导致了抗NMDA脑炎的诊断。这可能是我国首例此类疾病的病例报告之一。我们想强调高怀疑指数对于寻找任何出现精神症状和癫痫发作的儿童的器质性病因的重要性。
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Anti-NMDA Encephalitis: A Rare Encephalitis in a Child- A Case Report
Anti-NMDA encephalitis is second commonest cause of autoimmune encephalitis among children; however, it is hardly diagnosed and often not considered as one of the differentials when a child presents with encephalitis-related symptoms. In children, it presents mostly with seizures or psychiatric symptoms without prodrome. Here we present a six years old girl who presented with seizures and inappropriate behaviour. We investigated her in the line of viral encephalitis such as Japanese Encephalitis, which is very common in our region. However, results were not suggestive of Japanese Encephalitis and further investigations subsequently lead to diagnosis of antiNMDA encephalitis. This is probably one of the first case report of this disease in our country. We want to highlight the significance of high index of suspicion for looking out for an organic cause in any child who presents with psychiatric symptoms, along with seizures.
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