巴布亚省抗疟疾处方合理性的相关因素

I. S. Lingga, Sarhana Sarhana Rassya Aulyah Said, Dina Ayomi, Rusnaeni Rusnaeni, E. Gunawan, Nur Fadilah Bakri, E. Sianturi
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引用次数: 0

摘要

疟疾仍然是巴布亚的主要死亡原因,由于氯喹存在耐药性,建议联合使用二氢青蒿素-哌拉喹(DHP)和Primaquine(PQ)来取代氯喹。此外,认识到合理的处方和坚持可能是巴布亚预防疟疾死亡和耐药性治疗的首要任务。本研究旨在评估巴布亚省公共和私营部门抗疟处方的合理性。进行了这项横断面研究。本研究共纳入571个处方,其中超过一半的处方是合理的(65%)。这项研究主要是女性(65%)。超过一半的人被诊断为恶性疟原虫(54%),使用公立医院的转诊治疗(54%)和自称巴布亚人(50%)。根据疟疾类型,处方DHP和PQ的错误率分别为20%和18%。多元逻辑回归模型显示,女性比男性更容易接受不合理的处方(OR=1.549;95%可信区间=1.004-2.389)。患有恶性疟原虫的参与者增加了不合理处方的可能性(OR=1.641;95%置信区间=1.144-2.355)。需要有一个连续的策略来改善疟疾病例的获取和利用公共和私人卫生设施的管理。需要调查基于处方医生的性别不平等。提高医疗保健提供者的能力需要成为预防抗疟耐药性的优先事项。
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FACTORS ASSOCIATED WITH RATIONALITY OF ANTIMALARIA PRESCRIPTION IN PAPUA PROVINCE
Malaria remains a leading cause of death in Papua and combination of Dihydroartemisin -Piperaquine (DHP) and Primaquine (PQ) is recommended treatment to replace chloroquine out since chloroquine resistance present. Moreover, awareness of rational prescription and adherence may be the first priority in malaria treatment in preventing death and resistance in Papua. This study aimed to assess the rationality of antimalaria prescription in the public and private sectors of Papua Province. This cross-sectional study was conducted.  Overall, 571 prescriptions were included in this study and more than half of prescription was rational (65%). This study was predominantly female (65%). More than half was diagnosed by P. falciparum (54%), using referred using the public hospital for treatment (54%) and self-identified as Papuan (50%). According to type of malaria, incorrect of prescription DHP and PQ were 20% and 18%, respectively. The multiple logistic regression model showed that female was significantly associated to receive irrational of prescriptions than males (OR = 1.549; 95% CI =1.004-2.389). Participants who had P. falciparum increased the likelihood of irrational of prescriptions (OR= 1.641; 95% CI =1.144-2.355). There is a need to have a continuum strategy to improve access and utilization of malaria case management in both public and private health facilities. Inequality gender based on prescribers needs to be investigated. Competence improvement among healthcare providers needs to be a priority to prevent antimalarial resistance.
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