皮肤纤维肉瘤:病例报告系列

I. B. Suryawisesa, Oki P. Gotama
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引用次数: 0

摘要

隆突性皮肤纤维肉瘤(DFSP)是一种罕见的、无痛的、生长缓慢的浅表软组织恶性肉瘤,占所有恶性肿瘤的比例不到0.1%。DFSP的主要治疗方法是手术切除,即无肿瘤边缘的大面积局部切除(WLE)、莫氏显微手术(MMS)和部分或全部截肢。手术切除的目的是达到负切缘,从而减少局部复发率。这三个病例报告了大皮肤纤维肉瘤,最初是一个小结节,在大约一年内进展,随后进行了广泛的手术切除。对于大多数外科医生来说,由于肿瘤特殊的生长模式,其独特和具有挑战性的部分是采用同心切除术切除肿瘤。对于WLE和MMS手术技术来说,为了达到阴性切除边缘,无肿瘤边缘的宽度和浸润深度是完全切除时需要考虑的两个重要因素。辅助治疗,包括放疗和靶向治疗,用于不可切除、晚期或复发的肿瘤。
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Dermatofibrosarcoma: Case Report Series
Dermatofibrosarcoma protuberans (DFSP) is an uncommon, painless, slow-growth, superficial soft tissue malignant sarcoma corresponding to less than 0.1% of all malignancies. The primary treatment for DFSP is surgical excision, which is wide local excision (WLE) with tumor-free margins, Mohs micrographic surgery (MMS), and partial or total amputation. The goal of surgical excision is to achieve negative resection margins, thus reducing the local recurrence rate. These three cases reported large dermatofibrosarcoma, which began as a small nodule and progressed within approximately a year and were treated subsequently with wide excisions surgery. The unique and challenging part for most surgeons is removing the mass with a concentric excision due to its specific growth pattern. To achieve negative resection margins, the width of the tumor-free margins and infiltrating depth are two essential factors to be considered for complete excision for both WLE and MMS surgical techniques. Adjuvant therapy, including radiotherapy and targeted therapy, is reserved for unresectable, advanced stage, or recurrent tumors.
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