油葵叶乙醇提取物剥脱面膜的研制作为抗痤疮治疗

Irma Zarwinda, F. Fauziah, Jumirna Jumirna, A. Adriani
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引用次数: 0

摘要

本研究旨在制备和评价可剥离面膜作为胆道叶乙醇提取物(Averrhoa bilimbi L.)的抗痤疮功效。所用方法为实验,采用纸片扩散法通过对葡萄球菌表皮细菌的抑制试验对提取物进行评价。剥离掩模制剂添加浓度为7%(F1)、9%(F2)、11%(F3)的提取物,并且不使用提取物(F0)。剥离面膜制剂测试包括气味、颜色、刺激性检查的检测,以及剥离抗粉刺面膜功效的测定。这项研究是在班达亚齐的阿卡法玛和FKIP Unsyah的化学实验室进行的。在提取物浓度为100%、75%、50%和25%时,葡萄球菌表皮细菌的抑制区分别为15mm、12mm、11mm和10mm。这四种可剥离面膜配方是凝胶状的、均匀的、棕色的,具有独特的胆汁叶香味,不会刺激志愿者的皮肤。使用任何配方奶粉(F0、FI、FII和FIII)的面膜前后,痤疮的平均减少率分别为19.64%、22.63%、28.75%和50%。胆叶乙醇提取物的剥离面膜(Averrhoa bilimbi L.)是一种有效的抗痤疮治疗方法。
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THE FORMULATION OF PEEL-OFF MASK FROM THE ETHANOL EXTRACT OF BILIMBI LEAVES (Averrhoa blimbi L.) AS ANTI-ACNE TREATMENT
This research aims to formulate and assess the efficacy of the peel-off mask as an anti-acne of ethanol extract from bilimbi leaves (Averrhoa bilimbi L.).  The method used was an experiment, evaluating the extract through the inhibition test of Staphylococcus epidermis bacteria with the paper disk diffusion method. The peel-off mask formulation added the extract with a concentration of 7% (F1), 9% (F2), 11% (F3), and without using extract (F0). The Peel-off mask preparation testing includes the detection of scents, colours, irritation checks, and the determination of peel-off anti-acne mask efficacy. This study was carried out at Akafarma of Banda Aceh and the Chemistry laboratory of FKIP Unsyiah. The findings of the inhibition zone for Staphylococcus epidermis bacteria at extract concentrations of 100%, 75%, 50% and 25% were 15 mm, 12 mm, 11 mm and 10 mm, respectively. The four peel-off mask formulas were gel, homogeneous, brown, with the distinctive scent of bilimbi leaves, and did not irritate the volunteers’ skin. The average decline in acne before and after using the mask for any formula (F0, FI, FII, and FIII) was 19.64%, 22.63%, 28.75% and 50%, respectively. The peel-off mask of ethanol extract of bilimbi leaves (Averrhoa bilimbi L.) is effective as an anti-acne treatment.
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