印度北部三级保健中心蝎子中毒儿童的回顾性研究

R. Yadav, Muniba Alim, Y. Yadav, D. Singh, Alok Kumar
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引用次数: 1

摘要

背景:蝎子中毒是世界范围内常见的公共卫生问题,儿童发生严重心脏、呼吸和神经系统并发症的风险更大。蝎子中毒是一种可预防的危及生命的医疗事故。本研究旨在了解三级医院收治的儿童蝎子中毒的人口学参数、临床特征、并发症、结局和对哌唑嗪的反应。材料与方法:对2016年1月至2019年12月印度北方邦医科大学(UPUMS)儿科收治的52例有蝎子蜇伤史的儿科患者进行回顾性横断面研究。对所有患儿的临床资料、调查、治疗及预后进行评价。参数以百分比表示。结果:1 ~ 6岁儿童占多数,34例(65.38%),其中男性32例(61.53%),农村44例(84.62%),下肢蜇伤27例(51.92%),蜇伤间隙比(b/w)和住院时间< 6 h 28例(53.85%)。最常见的临床表现为疼痛46例(88.46%),常见并发症为肺水肿10例(19.23%)。绝大多数儿童在6小时内接受了吡唑嗪49(94.23%)26(51.02%),3-6次24(48.98%)。51例(98.0%)顺利出院,1例死亡。结论:儿童蝎子中毒是严重的环境健康危害,特别是在农村地区。蝎子中毒是一种严重的危及生命的紧急情况,从蝎子蜇伤中恢复是由给予普拉唑嗪治疗加速,预后良好,不使用蝎子抗蛇毒血清
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Retrospective Study of Children with Scorpion Envenomation in a Tertiary Care Center of North India
Background:  Scorpion envenomation is a common public health problem worldwide and children are at greater risk of developing severe cardiac, respiratory and neurological complications. Scorpion envenomation is a preventable life-threatening medical accident. This study aims at identifying the demographic parameters, clinical features, complications, outcome and response to prazosin in scorpion envenomation of children admitted at tertiary care hospital. Material and Methods: It was a retrospective cross sectionalstudy conducted on 52 pediatrics cases admitted in department of Paediatrics, Uttar Pradesh University of Medical Science (UPUMS), Saifai from Jan 2016 to Dec 2019 with history of scorpion sting. The clinical details, investigations, treatment and prognosis of all children were evaluated based on the scorpion envenomation. Parameters were expressed as percentage. Results: Majority of children were in the age group of 1 to 6 years 34 (65.38%) with 32 (61.53%) male and belonging to rural area 44 (84.62 %) with sting at lower limb 27 (51.92%) and gap b/w sting and hospitalization was < 6 hours 28 (53.85%). Most common clinical presentation was pain 46 (88.46%) and pulmonary edema 10 (19.23%) was common complications. Majority of children had received prazosin 49 (94.23%) within 6 hours 26 (51.02 %) with 3-6 doses 24 (48.98 %). 51 (98.0%) were successfully discharged and one patient was expired. Conclusion: Scorpion envenomation in children is a significant environmental health hazard especially in rural areas. Scorpion envenomation is an acute lifethreatening emergency, and recovery from scorpion sting is hastened by administration of prazosin therapy with excellent prognosis without use of scorpion antivenom
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期刊介绍: Asia Pacific Journal of Medical Toxicology (APJMT) aims to expand the knowledge of medical toxicology and tries to provide reliable information in this field for medical and healthcare professionals. APJMT mainly focuses on research related to medical toxicology issues in the Asia Pacific region and publishes articles on clinical and epidemiological aspects of toxicology, poisonings emergency care, addiction, drug interactions and adverse effects. The journal accepts and welcomes high quality papers in the form of original articles and rarely review articles, case reports and scientific letters relevant to medical practice in toxicology.
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