生物金属纳米颗粒:生物医学、分析、食品保鲜以及在其他消费品中的应用

IF 4.1 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Frontiers in Nanotechnology Pub Date : 2023-05-02 DOI:10.3389/fnano.2023.1175149
Ashwini Kumar, Sunny Shah, T. J. Jayeoye, Akash Kumar, A. Parihar, B. Prajapati, Sudarshan Singh, D. Kapoor
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引用次数: 6

摘要

生物金属纳米颗粒(BMNPs)是一种通过生物过程合成的纳米结构材料,因其体积小、比表面积大而受到广泛关注。由于BMNPs具有生态友好的合成方案、可持续性、生物相容性和多种生物医学应用,因此与化学合成的纳米颗粒相比具有许多优点。此外,由于金属纳米颗粒(MNPs)上的覆盖层具有优越的细胞相容性和稳定性,减少了毒副作用,使其成为传统药物递送方法更安全的替代方案。在BMNPs的一些有前景的应用中,它们的抗菌活性、重金属的分析传感以及在食品保鲜中的作用已被广泛探索。此外,除了药物传递和成像外,BMNPs还被研究用于治疗活性,如对皮肤和软组织医院病原菌的抗菌功效,以及在癌症治疗中靶向癌细胞。本综述介绍了几种与MNPs有关的表征技术,以及利用农业和生物材料合成MNPs的压缩方面,从而降低了合成成本并最大限度地减少了危险化学品的使用。综述了BMNPs的多种应用,包括生物医学、分析、食品保存和其他具有毒理学方面的消费品。
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Biogenic metallic nanoparticles: biomedical, analytical, food preservation, and applications in other consumable products
Biogenic metallic nanoparticles (BMNPs) are nanostructure materials synthesized through biological processes that have gained significant attention due to their small size and high surface area-to-volume ratio. BMNPs have several advantages over chemically synthesized ones due to their eco-friendly synthesis regimen, sustainability, biocompatibility, and diverse multifarious biomedical applications. Moreover, the superior cytocompatibility and stability due to the capping layer over metallic nanoparticles (MNPs), reduces the like hood of toxicity and side effects, making them a safer alternative to traditional drug delivery methods. Among several promising applications of BMNPs, their antibacterial activity, analytical sensing of heavy metals, and their roles in food preservations have been widely explored. In addition, to drug delivery and imaging, BMNPs have also been investigated for therapeutic activity such as antimicrobial efficacy against the skin and soft tissue nosocomial pathogens and targeting cancer cells in cancer therapy. The present review bestows several characterization techniques involved with MNPs and compressive aspects of the biogenic synthesis of MNPs using agricultural and biological materials, which reduces the cost of synthesis and minimizes the use of hazardous chemicals. The review also focuses on the multifold applications of BMNPs including biomedical, analytical, preservation of food, and in other consumable goods with toxicological aspects.
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来源期刊
Frontiers in Nanotechnology
Frontiers in Nanotechnology Engineering-Electrical and Electronic Engineering
CiteScore
7.10
自引率
0.00%
发文量
96
审稿时长
13 weeks
期刊最新文献
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