Madhu S. Giri, R. Shakya, D. Bista, Aastha Manandhar, Dikshya Giri
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引用次数: 0
摘要
背景和目的:心肌梗死后患者的药物依从性在世界各地都不理想。尽管在急性心肌梗死的诊断和治疗方面取得了重大进展,但它仍然是全球发病率和死亡率的主要原因,也是社会面临的重大治疗挑战。本研究的目的是研究药物依从性,并确定药物不良反应(ADR)对药物依从性的影响。方法:该研究是在尼泊尔Shahid Gangalal国家心脏中心(SGNHC)进行的一项单中心前瞻性研究。入选患者在出院后第6周在门诊部(OPD)就诊时进行随访。采用Morisky Green Levine(MGL)依从性量表对患者进行访谈,以确定药物依从性。对ADR进行了评估。数据在SPSS版本20中进行分析。结果:共有134名患者被纳入研究。研究表明,MI后患者对药物的依从性很高(92.5%),ADR与药物依从性无显著相关性。结论:患者对药物的依从性较高,ADR对药物依从性的影响不显著。
Medication Adherence in Post Myocardial Infarction Patients at Shahid Gangalal National Heart Centre
Background and Aims: Medication adherence among Post myocardial infarction (MI) patient is suboptimal all over the world. Although significant advances have been made in the diagnosis and management of Acute Myocardial Infraction, it is still a major cause of morbidity and mortality worldwide and significant therapeutic challenges to the society. The purpose of the study was to study the medication adherence and to identify the effect of adverse drug reaction (ADR) on medication adherence.
Methods: The study was a single center, prospective study carried out in Shahid Gangalal National Heart Centre (SGNHC) in Nepal. The enrolled patients were followed up at 6th weeks after discharge in outpatient department (OPD) visit. Patients were interviewed with Morisky Green Levine (MGL) adherence scale questionnaire to identify medication adherence. The ADR was assessed. Data were analyzed in SPSS version 20.
Results: A total of 134 patients were included in the study. The study showed post MI patient were highly adherent to medication (92.5%). ADR was not significantly associated with medication adherence.
Conclusion: Patients were highly adherent to medication and the effect of ADR on medication adherence was not significant.