局部晚期直肠癌新辅助放化疗的研究进展

中华放射肿瘤学杂志 Pub Date : 2020-03-15 DOI:10.3760/CMA.J.ISSN.1004-4221.2020.03.015

Yiru Wang, Yong Zhang, Tong Wu, Meizhu Shen

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引用次数: 0

摘要

术前新辅助放化疗(NCR)联合全肠系膜切除(TME)是局部晚期直肠癌的标准治疗模式。与术后NCR相比，术前NCR可提高肿瘤降期、括约肌保留率和局部控制率。术前NCR后达到病理完全缓解(pCR)的患者预后较好。本文综述了近年来术前NCR的研究进展。关键词:直肠肿瘤/放化疗;Radiochemotherapy新辅助;研究进展

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Research progresson neoadjuvant chemoradiotherapy for locally advanced rectal cancer

Preoperative neoadjuvant chemoradiotherapy (NCR) combined with total mesorectal excision (TME) is the standard treatment mode for locally advanced rectal cancer. Compared with postoperative NCR, preoperative NCR increases the tumor down-staging, sphincter-preserving rate and local control rate. Patients who attain pathological complete response (pCR) after preoperative NCR have better prognosis compared with their counterparts. This article reviews the research progress on preoperative NCR in recent years. Key words: Rectal neoplasm/radiochemotherapy; Radiochemotherapy, neoadjuvant; Research progress

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来源期刊

中华放射肿瘤学杂志

自引率

0.00%

发文量

6375

期刊介绍： The Chinese Journal of Radiation Oncology is a national academic journal sponsored by the Chinese Medical Association. It was founded in 1992 and the title was written by Chen Minzhang, the former Minister of Health. Its predecessor was the Chinese Journal of Radiation Oncology, which was founded in 1987. The journal is an authoritative journal in the field of radiation oncology in my country. It focuses on clinical tumor radiotherapy, tumor radiation physics, tumor radiation biology, and thermal therapy. Its main readers are middle and senior clinical doctors and scientific researchers. It is now a monthly journal with a large 16-page format and 80 pages of text. For many years, it has adhered to the principle of combining theory with practice and combining improvement with popularization. It now has columns such as monographs, head and neck tumors (monographs), chest tumors (monographs), abdominal tumors (monographs), physics, technology, biology (monographs), reviews, and investigations and research.