EQ-5D-5L仪器在登巴萨市癌症乳腺癌患者生活质量检测中的应用

Abdillah Mursyid, R. Haris, Dwi Endarti, Chairun Wiedyaningsih, Susi Ari Kristina
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摘要

癌症是世界上第二常见的癌症,也是每年癌症死亡的最大原因之一。测量癌症患者的生活质量可以改善治疗,并与患者的医疗参数一起成为预后因素。本研究旨在测量癌症患者的生活质量,并根据患者特点观察其对生活质量的影响。这项研究对93名癌症患者进行。数据是从登巴萨几个癌症社区的患者收集的,这些社区在3个月内(2019年1月至3月)进行了筛查。这项研究采用了一种横截面设计,使用了滚雪取样技术,涉及登巴萨几个癌症社区的癌症患者。患者的生活质量数据使用EuroQol-5维度5水平(EQ-5D-5L)通用仪器获得,并使用印尼值集转换为健康效用(效用)。使用独立t检验和多元回归对整个数据进行分析。结果显示,疼痛/不适和焦虑/抑郁是癌症患者最主要的问题(82,7%)。癌症患者的效用值为0.821±0.123,VAS值为74.41±11.67。根据患者的职业特征(p=0.035)、症状(p=0003)和癌症运动场(p=0.015),效用值存在显著差异。影响了登巴萨市20.5%的癌症乳腺癌患者的生活质量。
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Pengukuran Kualitas Hidup Pasien Kanker Payudara di Kota Denpasar Menggunakan Instrumen EQ-5D-5L
Breast cancer is the second most common cancer in the world and is one of the biggest causes of cancer deaths every year. Measurement of the quality of life in breast cancer patients could improve treatment and become a prognosic factor along with medical parameters for the patients. This study aims to measure the life quality of breast cancer patients and observe how it affects the life quality based on patient characteristics. The study was conducted on 93 breast cancer patients. Data were collected form patients in several breast cancer comunities in Denpasar which were carried outh within 3 months (January – March 2019). This study used a cross sectional design using a snowball sampling technique involving breast cancer patients in several cancer communities in Denpasar. The patient's life quality data was obtained using the EuroQol-5 Dimension-5 Level (EQ-5D-5L) generic instrument and conversion to health utility (utility) used the Indonesian value set. The entire data was analyzed using the independent t-test and multivariate regression. The results showed that pain/discomfort and anxiety/depression were the most dominant problem in breast cancer patients (82,7%). The utility value of breast cancer patients was 0.821±0.123 and the VAS value was 74.41±11.67. There was a significant difference in utility value based on patient characteristics of occupation (p=0.035), symptoms (p=0,003), and cancer stadium (p=0.015). Affected 20.5% of the quality of life of breast cancer patients in Denpasar city.
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