走向现代用于神经退行性疾病治疗的先进传感器:现状、挑战和前景

Akash Gautam
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引用次数: 6

摘要

神经退行性疾病(NDD)是神经系统的进行性退行性疾病,在世界范围内具有重要的社会影响。在初始阶段发现它们对于提供适当的治疗干预是必要的。生物传感器已成为检测和监测与神经系统疾病相关的物理化学变化的新一代工具之一。本文讨论了检测NDD生物标志物的不同先进传感器的现状和挑战。概述了利用纳米技术集成技术开发先进的生物传感器,主要是聚合物基功能纳米材料,并指出了这些生物传感器用于NDD检测和管理的前景。
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Towards Modern-Age Advanced Sensors for the Management of Neurodegenerative Disorders: Current Status, Challenges and Prospects
Neurodegenerative diseases (NDD) are progressive degenerative disorders of the neurological system with significant social impact worldwide. Their detection at the initial stage is necessary to provide proper therapeutic interventions. Biosensors have emerged as one of the next-generation tools for detecting and monitoring physiochemical changes associated with neurological disorders. This article discusses the current status and challenges of different state-of-the-art sensors which can detect NDD biomarkers. A brief overview of developing advanced biosensors with the help of nanotechnology integration, mainly polymer-based functional nanomaterials, has been mentioned as the prospect of these biosensors for NDD detection and management.
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