量子生物学研究与病理生理学和治疗机制:生物医学视角

Q2 Physics and Astronomy Quantum Reports Pub Date : 2022-04-04 DOI:10.3390/quantum4020011
L. Calvillo, V. Redaelli, Nicola Ludwig, Abdallah Barjas Qaswal, A. Ghidoni, A. Faini, D. Rosa, C. Lombardi, M. Pengo, P. Bossolasco, V. Silani, G. Parati
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引用次数: 6

摘要

量子生物学的最新进展表明它在生物医学研究中具有潜在的作用。电磁场、线粒体呼吸链中的质子泵送、t细胞受体(TCR)简并的量子理论、生物光子、焦磷酸盐或微管蛋白作为神经信息可能载体的理论、离子和质子的量子特性等相关研究,可能有助于理解一些严重的免疫、心血管和神经疾病的机制,而基于生化方法的经典生物医学研究,正在努力寻找新的治疗策略。因此,需要在医学知识方面取得突破,以提高对各种系统和器官之间复杂相互作用的理解,这些疾病是典型的。特别是,与免疫系统过度激活、自主神经系统(ANS)功能障碍在阻塞性睡眠呼吸暂停(OSA)综合征中的作用、离子通道功能障碍和遗传性心脏病的临床后果相关的问题,可能受益于量子生物学进步提供的新视角。总之,量子生物学可能提供一个有前途的生物物理理论体系,为病理生理学的理解和治疗策略提供基础。通过目前的工作,作者希望就这一重要话题展开一场建设性的多学科辩论。
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Quantum Biology Research Meets Pathophysiology and Therapeutic Mechanisms: A Biomedical Perspective
The recent advances of quantum biology suggest a potential role in biomedical research. Studies related to electromagnetic fields, proton pumping in mitochondrial respiratory chain, quantum theory of T-cell receptor (TCR)-degeneracy, theories on biophotons, pyrophosphates or tubulin as possible carriers for neural information, and quantum properties of ions and protons, might be useful for understanding mechanisms of some serious immune, cardiovascular, and neural pathologies for which classic biomedical research, based on biochemical approach, is struggling to find new therapeutic strategies. A breakthrough in medical knowledge is therefore needed in order to improve the understanding of the complex interactions among various systems and organs typical of such pathologies. In particular, problems related to immune system over-activation, to the role of autonomic nervous system (ANS) dysfunction in the obstructive sleep apnea (OSA) syndrome, to the clinical consequences of ion channels dysfunction and inherited cardiac diseases, could benefit from the new perspective provided by quantum biology advancement. Overall, quantum biology might provide a promising biophysical theoretic system, on which to base pathophysiology understanding and hopefully therapeutic strategies. With the present work, authors hope to open a constructive and multidisciplinary debate on this important topic.
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来源期刊
Quantum Reports
Quantum Reports Physics and Astronomy-Physics and Astronomy (miscellaneous)
CiteScore
3.30
自引率
0.00%
发文量
33
审稿时长
10 weeks
期刊最新文献
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