{"title":"监测细胞迁移","authors":"A. Bruinink","doi":"10.1142/9781860949302_0008","DOIUrl":null,"url":null,"abstract":"INTRODUCTION: Cells contacting an implant are affected by the implant surface. Latter interaction is an important key feature that determines the clinical success of implants. Beside the state of differentiation also the parameters cell shape, cell orientation, migration direction and migration velocity may be affected. Especially the latter two parameters (migration direction and migration velocity) may have consequences for the coverage of the implant by these cells. The monitoring of cell migration and its analysis are of key importance in order to elucidate the mechanisms on which (directed) cell migration is based.","PeriodicalId":49796,"journal":{"name":"Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":2.8000,"publicationDate":"2020-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1142/9781860949302_0008","citationCount":"0","resultStr":"{\"title\":\"Monitoring Cell Migration\",\"authors\":\"A. Bruinink\",\"doi\":\"10.1142/9781860949302_0008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"INTRODUCTION: Cells contacting an implant are affected by the implant surface. Latter interaction is an important key feature that determines the clinical success of implants. Beside the state of differentiation also the parameters cell shape, cell orientation, migration direction and migration velocity may be affected. Especially the latter two parameters (migration direction and migration velocity) may have consequences for the coverage of the implant by these cells. The monitoring of cell migration and its analysis are of key importance in order to elucidate the mechanisms on which (directed) cell migration is based.\",\"PeriodicalId\":49796,\"journal\":{\"name\":\"Molecular Imaging\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2020-05-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1142/9781860949302_0008\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Molecular Imaging\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1142/9781860949302_0008\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular Imaging","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1142/9781860949302_0008","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
INTRODUCTION: Cells contacting an implant are affected by the implant surface. Latter interaction is an important key feature that determines the clinical success of implants. Beside the state of differentiation also the parameters cell shape, cell orientation, migration direction and migration velocity may be affected. Especially the latter two parameters (migration direction and migration velocity) may have consequences for the coverage of the implant by these cells. The monitoring of cell migration and its analysis are of key importance in order to elucidate the mechanisms on which (directed) cell migration is based.
期刊介绍:
Molecular Imaging is a peer-reviewed, open access journal highlighting the breadth of molecular imaging research from basic science to preclinical studies to human applications. This serves both the scientific and clinical communities by disseminating novel results and concepts relevant to the biological study of normal and disease processes in both basic and translational studies ranging from mice to humans.