COVID-19疫苗决策分析

IF 1.2 Q3 MULTIDISCIPLINARY SCIENCES The EuroBiotech Journal Pub Date : 2021-06-01 DOI:10.2478/ebtj-2021-0017
D. Ozsahin, Mehmet Ilker Gelisen, M. Taiwo, Yasemin Agachan, Dorrin Rahi, B. Uzun
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引用次数: 17

摘要

摘要自2020年3月11日以来,全球都在与新冠肺炎大流行作斗争。仍有大量感染患者和死亡,目前还没有被证实的感染治疗方法。这导致了保护人们免受新冠肺炎感染的疫苗开发竞赛。截至2021年2月3日,共有289种实验性COVID-19疫苗正在开发中,其中66种处于不同阶段的临床试验中,其中20种处于第三阶段。本研究旨在根据剂量数、给药计划、储存优势、疗效和副作用等标准评估15种重要疫苗。在这个评估中,我们使用了模糊PROMETHEE方法,这是一种重要的多准则决策(MCDM)技术。标准的重要性级别是根据专家意见确定的。结果表明,根据选择的标准和每个标准的重要性水平,EpiVacCorona疫苗是预防新冠肺炎感染的最有效疫苗。所获得的结果可能会根据个人或专家的优先级而变化。由于使用不同的标准进行排名以及标准的不同权重,排名结果可能不同。这项研究还显示了所选疫苗的优势和劣势,以及MCDM技术在评估COVID-19疫苗方面的适用性。
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Decision Analysis of the COVID-19 Vaccines
Abstract The entire globe is struggling with the COVID-19 pandemic since March 11, 2020. There is still a large number of infected patients and death, and there is no proven treatment for the infection yet. This has led to the race in vaccine development to protect people from COVID-19 infection. As of February 3, 2021, there were 289 experimental COVID -19 vaccines in development, 66 of which were in clinical trials with different phases, and 20 of them were in phase 3. This study aims to evaluate 15 important vaccines based on criteria such as the dose number, dosing schedule, storage advantages, efficacy, and side effect. In this evaluation, we use the fuzzy PROMETHEE approach, which is an important Multi-Criteria Decision Making (MCDM) technique. The importance level of the criteria is determined based on expert opinion. The result shows that the EpiVacCorona vaccine is the most effective vaccine to prevent COVID-19 infections based on the selected criteria and the importance level of each criterion. The result obtained may change based on individual or expert’s priorities. Due to the use of different criteria for the ranking and different weightings of the criteria, the ranking result may differ. This study also shows the strengths and weaknesses of the selected vaccines and the applicability of the MCDM technique for the evaluation of COVID -19 vaccines.
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来源期刊
The EuroBiotech Journal
The EuroBiotech Journal Agricultural and Biological Sciences-Food Science
CiteScore
3.60
自引率
0.00%
发文量
17
审稿时长
10 weeks
期刊最新文献
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