{"title":"C反应蛋白/白蛋白比值对成人并发阑尾炎的预测价值","authors":"Xin Zhao, Jian Yang, Jun Li","doi":"10.1515/labmed-2023-0069","DOIUrl":null,"url":null,"abstract":"Abstract Objectives The purpose of this study was to analyze the role of C-reactive protein/albumin ratio (CRP/ALB) in the diagnosis of complicated appendicitis in adults. Methods A retrospective analysis of 202 patients with acute appendicitis admitted to the Emergency Department of Weifang People’s Hospital between January 2021 and December 2022 was conducted. Patients were classified into complicated appendicitis group (CA) and non-complicated appendicitis group (NCA) based on postoperative pathological diagnosis, and the two groups were compared in terms of preoperative age, gender, white blood cell count (WBCC), C-reactive protein/albumin ratio (CRP/ALB), serum sodium (Na), and fibrinogen (FIB). Results The 202 cases of acute appendicitis in this study, 36.6 % (n=74) were CA. Multivariate logistic regression analysis showed that CPR/ALB (p≤0.001), FIB (p<0.001), and Na (p=0.011) were risk factors for complicated appendicitis. The results of receiver operating characteristic (ROC) analysis, conducted to evaluate the role of CRP/ALB, Na, and FIB in detecting CA, showed that the area under the curve (AUC) of CRP/ALB was 0.871, which was higher than that of FIB and Na. CRP/ALB ratio ≥1.04 was an important indicator for predicting complicated appendicitis, with a sensitivity of 78.2 % and specificity of 84.7 %. Conclusions CRP/ALB ratio can serve as a good indicator for predicting complicated appendicitis.","PeriodicalId":55986,"journal":{"name":"Journal of Laboratory Medicine","volume":null,"pages":null},"PeriodicalIF":1.1000,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The predictive value of the C-reactive protein/albumin ratio in adult patients with complicated appendicitis\",\"authors\":\"Xin Zhao, Jian Yang, Jun Li\",\"doi\":\"10.1515/labmed-2023-0069\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract Objectives The purpose of this study was to analyze the role of C-reactive protein/albumin ratio (CRP/ALB) in the diagnosis of complicated appendicitis in adults. Methods A retrospective analysis of 202 patients with acute appendicitis admitted to the Emergency Department of Weifang People’s Hospital between January 2021 and December 2022 was conducted. Patients were classified into complicated appendicitis group (CA) and non-complicated appendicitis group (NCA) based on postoperative pathological diagnosis, and the two groups were compared in terms of preoperative age, gender, white blood cell count (WBCC), C-reactive protein/albumin ratio (CRP/ALB), serum sodium (Na), and fibrinogen (FIB). Results The 202 cases of acute appendicitis in this study, 36.6 % (n=74) were CA. Multivariate logistic regression analysis showed that CPR/ALB (p≤0.001), FIB (p<0.001), and Na (p=0.011) were risk factors for complicated appendicitis. The results of receiver operating characteristic (ROC) analysis, conducted to evaluate the role of CRP/ALB, Na, and FIB in detecting CA, showed that the area under the curve (AUC) of CRP/ALB was 0.871, which was higher than that of FIB and Na. CRP/ALB ratio ≥1.04 was an important indicator for predicting complicated appendicitis, with a sensitivity of 78.2 % and specificity of 84.7 %. Conclusions CRP/ALB ratio can serve as a good indicator for predicting complicated appendicitis.\",\"PeriodicalId\":55986,\"journal\":{\"name\":\"Journal of Laboratory Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2023-08-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Laboratory Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1515/labmed-2023-0069\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICAL LABORATORY TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Laboratory Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1515/labmed-2023-0069","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}
The predictive value of the C-reactive protein/albumin ratio in adult patients with complicated appendicitis
Abstract Objectives The purpose of this study was to analyze the role of C-reactive protein/albumin ratio (CRP/ALB) in the diagnosis of complicated appendicitis in adults. Methods A retrospective analysis of 202 patients with acute appendicitis admitted to the Emergency Department of Weifang People’s Hospital between January 2021 and December 2022 was conducted. Patients were classified into complicated appendicitis group (CA) and non-complicated appendicitis group (NCA) based on postoperative pathological diagnosis, and the two groups were compared in terms of preoperative age, gender, white blood cell count (WBCC), C-reactive protein/albumin ratio (CRP/ALB), serum sodium (Na), and fibrinogen (FIB). Results The 202 cases of acute appendicitis in this study, 36.6 % (n=74) were CA. Multivariate logistic regression analysis showed that CPR/ALB (p≤0.001), FIB (p<0.001), and Na (p=0.011) were risk factors for complicated appendicitis. The results of receiver operating characteristic (ROC) analysis, conducted to evaluate the role of CRP/ALB, Na, and FIB in detecting CA, showed that the area under the curve (AUC) of CRP/ALB was 0.871, which was higher than that of FIB and Na. CRP/ALB ratio ≥1.04 was an important indicator for predicting complicated appendicitis, with a sensitivity of 78.2 % and specificity of 84.7 %. Conclusions CRP/ALB ratio can serve as a good indicator for predicting complicated appendicitis.
期刊介绍:
The Journal of Laboratory Medicine (JLM) is a bi-monthly published journal that reports on the latest developments in laboratory medicine. Particular focus is placed on the diagnostic aspects of the clinical laboratory, although technical, regulatory, and educational topics are equally covered. The Journal specializes in the publication of high-standard, competent and timely review articles on clinical, methodological and pathogenic aspects of modern laboratory diagnostics. These reviews are critically reviewed by expert reviewers and JLM’s Associate Editors who are specialists in the various subdisciplines of laboratory medicine. In addition, JLM publishes original research articles, case reports, point/counterpoint articles and letters to the editor, all of which are peer reviewed by at least two experts in the field.