以绿茶提取物为抗氧化剂的电化学合成生物纳米银

D. Hermanto, N. Ismillayli, Irmawanti Irmawanti, Ilfa Fathulloh, Diska Nila, U. K. Zuryati, H. Muliasari, R. Wirawan
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引用次数: 2

摘要

摘要抗氧化剂在癌症预防中的作用导致了其合成的发展,包括绿色茶盖银纳米颗粒(AgNP),这是一种天然抗氧化剂。首次采用当地绿茶提取物,以纯银丝为原料,电化学合成了生物AgNPs,其特征峰在420nm处。该方法缩短了反应时间,产生了长期稳定且尺寸分布窄的纳米颗粒。TEM分析证实了平均尺寸为~17nm的球形AgNP。此外,FTIR分析和植物化学分析表明,类黄酮和萜类化合物的-OH基团对该过程负责。DPPH方法证实AgNPs的抗氧化活性高于提取物,IC50为54.99ppm。因此,该方法可以用于治疗有害疾病的药物产品的大规模生产。
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Electrochemically Synthesized Biogenic Silver Nanoparticles Using Green Tea Extract as a Promising Antioxidant
Abstract The role of an antioxidant in cancer prevention has led to the development of its synthesis, including green tea-capped silver nanoparticles (AgNPs), which are natural antioxidants. The biogenic AgNPs were synthesized electrochemically from pure silver wire using local green tea extract for the first time, with a characteristic peak at 420 nm. The method shortened the reaction time and produced long-term stable and narrow-size distribution nanoparticles. The spherical AgNP with an average size of ~17 nm was confirmed in TEM analysis. Furthermore, FTIR analysis and phytochemical assays revealed that the -OH group of flavonoids and terpenoids was responsible for the process. The DPPH method confirmed the higher antioxidant activity of AgNPs than extract, with an IC50 of 54.99 ppm. Hence, the method can be implemented for the large-scale production of pharmaceutical products in treating harmful diseases.
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来源期刊
Karbala International Journal of Modern Science
Karbala International Journal of Modern Science Multidisciplinary-Multidisciplinary
CiteScore
2.50
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0.00%
发文量
54
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