10 mv光子束前列腺放射治疗计划的RapidPlan模型

IF 0.3 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Journal of Radiotherapy in Practice Pub Date : 2022-10-12 DOI:10.1017/S1460396922000267
F. Pupillo, M. Piliero, M. Casiraghi, L. Bellesi, S. Presilla
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引用次数: 0

摘要

摘要简介:RapidPlan是一种放射治疗计划工具,它使用已批准计划的数据集来预测剂量分布,并自动生成剂量-体积约束,以优化新计划。本研究比较了使用10-MV光子束治疗前列腺癌症的三种模型构建策略。方法:比较3种前列腺治疗模型:6X型、10X型和6X改良型。Model6X已经在我们部门使用,并接受了基于6-MV光子束的治疗计划培训。Model10X接受了基于10-MV光子束的治疗计划培训,并由经验丰富的医学物理学家手动优化。最后,在Model6X自动创建的计划上训练Model6Xrefined,但使用10-MV光子束。这三个模型被用于生成25个具有10-MV光子束的新计划。结果:Model10X生成的计划中,膀胱PTV和直肠PTV体积的平均剂量降低了2Gy,膀胱和直肠体积的V15Gy降低了8%,尽管监测单元的数量平均增加了170个。结论:在手动优化计划上训练的模型生成了具有更高正常组织保留率的计划。然而,模型构建是一个耗时的过程,因此应该进行成本效益平衡。
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RapidPlan models for prostate radiotherapy treatment planning with 10-MV photon beams
Abstract Introduction: The RapidPlan is a radiotherapy planning tool that uses a dataset of approved plans to predict the dose distribution and automatically generates the dose–volume constraints for optimisation of the new plan. This study compares three strategies of model building for the treatment of prostate cancer with the 10-MV photon beam. Methods: Three models for prostate treatment were compared: Model 6X, Model10X and Model6Xrefined. Model6X is already used in our department and was trained on treatment plans based on the 6-MV photon beam. Model10X was trained on treatment plans based on the 10-MV photon beam and manually optimised by an experienced medical physicist. Finally, Model6Xrefined was trained on plans automatically created by the Model6X, but using the 10-MV photon beam. The three models were used to generate 25 new plans with the 10-MV photon beam. Results: Model10X generated plans with 2 Gy lower mean dose to bladder-PTV and rectum-PTV volumes and 8% lower V15Gy at bladder and rectum volumes, although the number of monitor units increased by 170 on average. Conclusions: The model trained on manually optimised plans generated plans with higher normal tissue sparing. However, model building is a time-consuming process, so a cost–benefit balance should be performed.
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来源期刊
Journal of Radiotherapy in Practice
Journal of Radiotherapy in Practice RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
0.80
自引率
0.00%
发文量
36
期刊介绍: Journal of Radiotherapy in Practice is a peer-reviewed journal covering all of the current modalities specific to clinical oncology and radiotherapy. The journal aims to publish research from a wide range of styles and encourage debate and the exchange of information and opinion from within the field of radiotherapy practice and clinical oncology. The journal also aims to encourage technical evaluations and case studies as well as equipment reviews that will be of interest to an international radiotherapy audience.
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