人鼻窦骨组织形态学参数的复杂自动测定

Q3 Computer Science Open Bioinformatics Journal Pub Date : 2021-11-19 DOI:10.2174/18750362021140100130
A. Nechyporenko, R. Radutny, V. Alekseeva, G. Titova, V. Gargin
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引用次数: 2

摘要

自动化分析的应用目前在科学技术的各个领域都处于领先地位。我们研究的目的是提供一种复杂的自动测定人体鼻窦骨组织形态参数的方法。这项研究涉及50名年龄在20至60岁之间的患者,包括男性和女性,他们没有鼻窦炎症或其他病理过程的迹象。截面的高对比度图像中的骨密度可以通过颜色强度的波动来确定。在清洁之前,使用高斯函数对图像进行模糊处理。由于这种操作,图像变得不那么清晰,小细节合并。一种被称为Connie边界检测器的算法已经得到了广泛的应用。表示轮廓的曲线可以垂直、水平或以不同角度对角延伸。垂直和水平通过的曲线的方向的检测并不复杂,并且对于对角线方向的曲线,使用Sobel算子,其中垂直方向Gy和水平方向Gx作为一阶导数的值。骨组织区域的选择需要评估沿着该区域长边的亮度梯度。为了清楚起见,该操作以图形方式显示。在这项工作的范围内,我们开发了一种通过测量骨密度和厚度来自动综合评估PNSs壁形态结构的方法。
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Complex Automatic Determination of Morphological Parameters for Bone Tissue in Human Paranasal Sinuses
Application of automated analysis currently occupies a leading position in every field of science and technology. The aim of our study was to provide a complex automatic determination of morphological parameters for bone tissue in human paranasal sinuses. The study involved 50 patients aged 20 to 60, male and female without signs of inflammatory or other pathological processes in the paranasal sinuses (PNSs). Bone density in a high-contrast image of the section can be determined by fluctuations in colour intensity. Before cleaning, the image is blurred using the Gaussian function. As a result of this operation, the images become less clear and small details merge. An algorithm known as the Connie Border Detector has found widespread use. The curves denoting the contours can run vertically, horizontally or diagonally at different angles. Detection of the direction of curves passing vertically and horizontally is not complicated, and for curves of the diagonal direction, the Sobel operator is used, with the vertical direction Gy and horizontal Gx as the value of the first derivative. Selection of areas of bone tissue requires the assessment of brightness gradient along the long side of the area. For clarity, this operation was shown graphically. Within the scope of this work, we have developed a method for an automatic comprehensive assessment of the morphological structure of the PNSs walls with the measurement of bone density and thickness.
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来源期刊
Open Bioinformatics Journal
Open Bioinformatics Journal Computer Science-Computer Science (miscellaneous)
CiteScore
2.40
自引率
0.00%
发文量
4
期刊介绍: The Open Bioinformatics Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews, letters, clinical trial studies and guest edited single topic issues in all areas of bioinformatics and computational biology. The coverage includes biomedicine, focusing on large data acquisition, analysis and curation, computational and statistical methods for the modeling and analysis of biological data, and descriptions of new algorithms and databases. The Open Bioinformatics Journal, a peer reviewed journal, is an important and reliable source of current information on the developments in the field. The emphasis will be on publishing quality articles rapidly and freely available worldwide.
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