Isolation and identification of two flavonoid compounds from acclimatized Angelica acutiloba kitagawa growing in Vietnam

Traditional Vietnamese Medicine has its own development based on the local endemic herbs, but it also inherits from Traditional Chinese Medicine using Chinese herbal medicines. Throughout the history of cultural exchange between two countries, the adoption of Chinese Danggui, Angelica sinensis (Oliv.) Diels., has been made by Vietnamese traditional medicine practitioners for a long time. However, the acclimatization has never been successful. Japanese Danggui, or Angelica acutiloba Kitagawa, is recently being acclimatized and cultivated in several Vietnamese regions. Despite the huge climate change between the two countries, the herb adapted exquisitely well to the humid tropical climate. However, so far, there are no studies that have evaluated the effect of acclimatization on the overall quality of this medicinal herb. The aim of our study is screening secondary metabolites of this acclimatized herb for new natural compound(s), if any. The analysis of flavonoid fraction from this herb led to the identification of two known compounds which previously have not been isolated from this species elsewhere. This detection showed that the herb has reacted to the new environment.