平衡障碍和甲状腺功能减退:一个值得记住的罕见原因

IF 0.2 Q4 OTORHINOLARYNGOLOGY ENT Updates Pub Date : 2019-12-20 DOI:10.32448/entupdates.633311
A. Kul, A. Bilen, N. Bilge, Köksal Sarıhan, H. Uzkeser, R. Dayanan, Fatih Baygutalp
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引用次数: 0

摘要

目的:本研究旨在评估甲状腺功能减退患者的平衡障碍和跌倒的潜在危险因素,以及姿势稳定性和跌倒风险。方法:记录参与者的性别、年龄、体重指数(BMI)、过去一年的跌倒史、国际跌倒疗效量表(FES-I)、神经性疼痛诊断问卷(DN4)和临床症状。稳定性指数(SI)、体重分布指数(WDI)和跌倒风险分析通过客观的计算机动态姿势描记术进行姿势稳定性。结果:50名患者的年龄和性别(平均年龄:41.7±11岁;年龄范围:19-61岁)与47名健康(甲状腺功能正常)对照组(平均年龄39±9.6岁;年龄区间:23-60岁)相匹配。除FES-I、DN4和NO-SI外,患者组的所有SI、HL-WDI和跌倒风险评分均显著较高。此外,除晨僵外,其他症状的出现率更高(p 0.05)。然而,审美障碍症状的存在、跌倒史与整体SI和HL-WDI值之间存在轻微的正相关(r>0.3和p<0.05),平衡变得紊乱,跌倒的风险增加。跌倒风险的增加与甲状腺功能减退有关,但与FT4或TSH水平或其他评估因素无关。
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Balance disorders and hypothyroidism: A rare cause worth remembering
Objectives : This study aimed to evaluate balance disorders and potential risk factors for falling in patients with hypothyroidism, as well as postural stability and the risk of falling. Methods : The participants' sex, age, body mass index (BMI), falls history in the past one year, and Falls Efficacy Scale - International (FES-I), Neuropathic Pain Diagnostic questionnaire (DN4) and clinical symptoms were recorded. The stability index (SI), weight distribution index (WDI) and falls risk analysis were performed for postural stability by objective computerised dynamic posturography. Results : 50 patients were matched for age and sex (mean age:41.7±11 years; age range:19-61 years) with 47 healthy (euthyroid) controls (mean age:39±9.6 years; age range:23-60 years). All SI, HL-WDI and falls risk scores, except FES-I, DN4 and NO-SI, were significantly higher in the patient group. In addition, other symptoms were present at a higher rate, with the exception of morning stiffness (p 0.05). However, there was a slight positive correlation between the existence of paraesthetic symptoms, a history of falling, and the overall SI and HL-WDI values (r>0.3 and p<0.05). Conclusions: It was determined that, as postural stability is affected in cases of hypothyroidism, balance becomes disordered and the risk of falls increases.  This increase in the risk of falls was associated with being hypothyroid, but not with FT4 or TSH levels or the other factors evaluated.
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ENT Updates
ENT Updates OTORHINOLARYNGOLOGY-
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