基于fMRI测量的血流动力学模型求解算法

Md. Roni Islam, Sheikh Md. Rabiul Islam
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引用次数: 1

摘要

背景与目的在生物医学工程领域,血流动力学模型是成功监测和预测脑活动的基本方法。血流动力学模型描述了人脑中血流体素的内部情况,是脑相关研究活动中最流行的假设。血流动力学模型具有非线性性质。这类血流动力学模型的求解是一项值得研究的工作。方法利用功能磁共振成像图像求解模型的算法有很多;最近,吴海峰提出了一种新的求解血流动力学模型的方法——混合平方根立方卡尔曼滤波和混合平方根立方平滑(CSCKF-CSCKS)。该模型的相对准确度为84%。在本文中,为了达到更好的准确性,对数据分析和模型算法进行了不同的呈现,并发现了之前没有提到的新结果。结果本实验的数据分析表明,如果最大迭代次数增加3倍,在两种情况下使用的fMRI测量类型下,求解血流动力学模型的总体精度提高了5.76%。我们还提供了一个计算相对误差的公式,以评估这些估计的性能。结论推荐利用fMRI图像求解血流动力学模型的算法,可以更好地估计模型的生物物理参数和隐藏状态。因此,我们将通过使用功能磁共振成像图像,找到更准确的人类大脑特定区域的场景。
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The hemodynamic model solving algorithm by using fMRI measurements

Background and objective

The hemodynamic model is a fundamental approach for successfully monitoring and possibly forecasting brain activities in the biomedical engineering field. The hemodynamic model describes the inner scenario of a blood flowing voxel in a human brain and it is most popular hypothesis on the brain related research activities. The hemodynamic model has nonlinearities in nature. The solution of such type hemodynamic model is researchable work.

Method

There are many model solving algorithms by using fMRI images; recently, Haifeng Wu presented Confounds Square-root Cubature Kalman Filtering and Confounds Square-root Cubature Smoothing (CSCKF-CSCKS) is the latest approach for solving hemodynamic models. The relative accuracy of this model was shown 84%. In this article, in order to achieve better accuracy, the data analysis and model algorithms are presented differently and find new result that was not mentioned earlier.

Result

The data analysis of this experiment shows that if the maximum number of iterations increases three times, the overall accuracy for solving the hemodynamic model raises by 5.76% under the exact type of fMRI measurements used in both cases. We also represent a formula for calculating a relative error to evaluate the performance of these estimations.

Conclusion

A recommendation is made for solving the hemodynamic model algorithm by using fMRI images to get better performance for estimating the model's biophysical parameters and hidden states. As a result, we will find out more accurate scenario of a specific region of human brain by using fMRI images of that region.

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来源期刊
Neuroscience informatics
Neuroscience informatics Surgery, Radiology and Imaging, Information Systems, Neurology, Artificial Intelligence, Computer Science Applications, Signal Processing, Critical Care and Intensive Care Medicine, Health Informatics, Clinical Neurology, Pathology and Medical Technology
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