Rate and Risk Profile of Deep Venous Thrombosis in Pregnancy and Postpartum Period Among Sudanese Women

Background: Deep venous thrombosis (DVT) during pregnancy is associated with high mortality, morbidity, and costs. DVT can also result in long-term complications that include post thrombotic syndrome (PTS) adding to its morbidity. Objective: To determine rate, timing and risk profile of deep venous thrombosis during pregnancy and puerperium among Sudanese women. Methodology : It was prospective case control and hospital-based study carried out at Shendi Teaching and Elmec-Nimir University Hospitals -Sudan from March 2017 to March 2018. Seventy-eight pregnant women or in puerperium with Doppler confirmed deep venous thrombosis were enrolled in the study, representing the main study group, while another 156 pregnant women without DVT were selected as the control group. Results: The current study showed the frequency of DVT was (0.622%), 78 out of 12,542 deliveries during the whole study period, with (0.176%) and (0.446%) occurring antenatal and postnatal respectively. The rate was 622 DVT per 100,000 births. This study revealed that women who are primigravida, had positive family history of VTE, had past history of DVT, had Anti phospholipids, anemia and delivered by C/S showed statistically significant association with DVT. Conclusions: The prevalence of DVT in our study was 622 per 100 000 births per year in pregnant and postpartum women. There is an urgent need for prophylaxis measures against DVT for pregnant women who found at higher risk for DVT.