三维导航立体定向肝消融的叙述性回顾——我们还需要微创肝外科医生吗?

R. Bale, P. Schullian, Amilcar Alzaga
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引用次数: 1

摘要

消融是一种令人兴奋的替代手术的治疗原发性和转移性肝癌癌症的意向性治疗方法。然而,除了极少数患者外,传统技术并没有达到与手术同等的肿瘤学结果。我们在这里讨论了立体定向技术在RFA中的应用,并总结了该方法的可用临床证据,使消融治疗的肿瘤学结果与手术相当。即使取得了有希望的结果,我们也是唯一一个采用这种方法的机构,而且类似的方法只在全球少数几个中心进行。其原因是多因素的,但经皮消融术的报销似乎是该技术成为主流的最重要限制因素。尽管如此,要回答的问题是:立体定向肝切除术会取代微创肝切除术吗?在我们看来,立体定向肝切除将改变我们治疗原发性和转移性肝癌癌症的方式,但理想情况下,通过增加另一种可行且一致的微创选择。其目的是为更多的患者提供有治疗意图的治疗,并使开放式手术成为最后的选择。要做到这一点,外科医生和介入放射科医生必须共同努力,创造临床证据,并知道如何实现这一点。
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Narrative review of 3D navigated stereotactic liver ablation—do we still need a minimally invasive liver surgeon?
Ablation is an exciting alternative to surgery as a curative intent treatment for primary and metastatic liver cancer. However, conventional techniques have not achieved oncologic outcomes equal to surgery except in a minimal subset of patients. We discuss here our use of a stereotactic technique for RFA and summarize the available clinical evidence for this approach to make oncological outcomes of ablation therapy comparable to surgery. Even with promising results, we are the only institution performing this approach, and similar approaches are only made in a few centers worldwide. The causes for that are multifactorial, but reimbursement of percutaneous ablation seems to be the most significant limiting factor for this technology becoming mainstream. Nonetheless, the question to answer is: will stereotactic liver ablation replace minimally invasive liver resection? In our opinion, stereotactic liver ablation will change the way we treat primary and metastatic liver cancer, but ideally, by adding another viable and consistent minimally invasive option. The objective is offering curative intent treatments to more patients and making open procedures become a last resort option. To get there, surgeons and interventional radiologists have to work together to create the clinical evidence and knowhow to make this a reality.
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