犬退行性腰骶管狭窄术后脑脊液的动态变化

Ilya F. Vilkowysky
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摘要

犬退行性腰骶管狭窄矫正术后脑脊液动力学参数是一个重要的诊断方面,可以监测手术后动物状态的变化。脑脊液的准确分析为患者的神经健康提供了广泛的信息。评估应包括宏观、定量和微观分析。细胞计数是疾病最重要和最敏感的指标。本研究的目的是确定退行性腰骶管狭窄矫正术后脑脊液的变化。在本研究中,有9只不同品种的狗,年龄从2岁到8岁(实验组),3只健康的远缘狗在5岁以下体检时获得的脑脊液和外周血指标作为对照。根据B.P.Meij,N.Bergknut进行手术干预,包括L7-S1椎弓的背侧通路、软组织剥离、背韧带剥离、S1、L7颅骨关节突中通道的形成。从每只动物中,在手术后第1-3天、第12-15天和第27-30天取三份利口酒进行检查三次。在服用后30分钟内进行脑脊液研究。根据所获得的数据,发现狗在腰骶管狭窄矫正术后的液体细胞组成在生理正常范围内,脑脊液中未检测到红细胞。手术犬的有核细胞数量在手术后第1-3天最高。在手术后的第12-15天,实验组和对照组动物的胞嘧啶增加了1.27个细胞/l。在手术后第27-30天,与对照组相比,实验组狗的胞嘧啶减少0.45个细胞/l。脑脊液分析有助于对术后动物状况的诊断评估。然而,应该记住的是,结果很少针对任何特定的情况,应该根据临床和其他诊断结果进行解释。
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Dynamics of cerebrospinal fluid in correction of degenerative lumbosacral stenozis during the postoperative period in dogs
Dynamics of cerebrospinal fl parameters in postoperative period during correction of degenerative lumbosacral stenosis in dogs is an important diagnostic aspect that allows monitoring changes in the state of animals after surgery. An accurate analysis of cerebrospinal fl id provides a wide range of information about the patients neurological health. The assessment should consist of macroscopic, quantitative and microscopic analyses. Сell count is the most important and potentially sensitive indicator of disease. The aim of this study was to determine changes in the cerebrospinal fluid during the postoperative period in the correction of degenerative lumbosacral stenosis. In the study, there were 9 dogs of various breeds, aged from 2 to 8 years (experimental group), the indicators of cerebrospinal fluid and peripheral blood of 3 healthy outbred dogs obtained as a result of medical examination at the age of up to 5 years were used as a control. Surgical intervention was carried out according to the B.P. Meij, N. Bergknut, which consists in dorsal access to the L7-S 1 vertebral arches, soft tissue dissection, dissection of the dorsal ligament, formation of channels in the cranial articular processes of S 1, L7. From each animal, three liquorograms were taken for examination three times on days 1-3 after surgery, on days 12-15 and 27-30 after surgery. The study of cerebrospinal fluid was performed within 30 minutes after taking. As a result of the data obtained, it was found that the cellular composition of the liquor of dogs in the postoperative period of correction of lumbosacral stenosis was within the physiological norm, erythrocytes in the cerebrospinal fluid were not detected. The number of nucleated cells in operated dogs was the highest on days 1-3 after surgery. On the 12th-15th day after the operation, cytosis in the experimental and control groups of animals was 1.27 cells/l more. On days 27-30 after surgery, cytosis in dogs in the experimental group was lower by 0.45 cells/l compared to the control. Analysis of cerebrospinal fluid can help in the diagnostic assessment of the condition of animals in the postoperative period. However, it should be borne in mind that results are rarely specific to any particular condition and should be interpreted in the light of clinical and additional diagnostic findings.
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