厄瓜多尔基多一家医院单一等候名单上的患者和肾脏移植捐赠者的流行病学概况

Q4 Medicine Transplantation Reports Pub Date : 2021-09-01 DOI:10.1016/j.tpr.2021.100075
Sueny Paloma Lima dos Santos , Maria Lorena Arias Castro , Gonzalo Javier Pullas-Tapia , Jorge Washington Huertas Garzon
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引用次数: 0

摘要

背景。在厄瓜多尔,估计有超过800人在等待器官移植。因此,本研究的目的是描述肾移植等待名单上的患者和供体的流行病学概况。对2012年至2019年期间接受移植手术的67名患者进行了横断面回顾性研究。我们包括来自已故和活体捐献者的器官接受者。研究了患者和供体的年龄、透析至移植的时间、供体类型、慢性肾衰竭的原因、合并症、透析类型、冷缺血时间、供体和患者的血型、相容性、移植后并发症、移植物功能延迟、免疫抑制等。男性45例,年龄46.80±11.48岁。女性22例,年龄40.45±12.9岁。供体平均年龄40.71±13.28岁。55.2%的患者CKD病因不明。第二常见的是糖尿病肾病和狼疮肾炎,均为7.5%。92.4%的患者接受了已故供者的肾脏,平均年龄为45.2±13.9岁。相反,只有7.6%的人有来自活体供体的肾脏。了解流行病学概况对卫生战略具有重要意义。它可以为这个名单中最脆弱的人口提供医疗保健,并努力降低发病率和死亡率。
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Epidemiological profile of patients on a single waiting list and donors for a kidney transplant in a hospital in Quito, Ecuador

Background

. In Ecuador, it is estimated that more than eight hundred people are on the waiting list for organ transplants. For this reason, the aim of this study is to describe the epidemiological profile of patients on the waiting list and donor for a kidney transplant.

Methods

. A cross-sectional retrospective study was performed on 67 patients who underwent transplants between 2012 and 2019. We included recipients of organs from both deceased and living donors. Age of patients and donors, period in which they underwent dialysis until the transplant, type of donor, cause of chronic kidney failure, comorbidities, type of dialysis, cold ischemia time, blood-type of donors and patients, compatibility, complications after transplant, delayed graft function, and immunosuppression, were studied.

Results

. A total of 45 patients were male, with age 46.80 ± 11.48 years old. Twenty-two were females, with age of 40.45 ± 12.9 years old. The mean age of the donor was 40.71 ± 13.28 years old. 55.2% of the etiology to develop CKD in patients was unknown. The second most prevalent were diabetic nephropathy and lupus nephritis, both of which registered 7.5%. Furthermore, 92.4% received kidneys from deceased donors, and the mean age of those recipients was 45.2 ± 13.9 years old. Conversely, only 7.6% had kidneys from living donors.

Conclusions

. The importance of knowing the epidemiological profile is for health strategies. It can be developed for the medical care of the most vulnerable population within this list, and try to reduce morbidity and mortality.

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来源期刊
Transplantation Reports
Transplantation Reports Medicine-Transplantation
CiteScore
0.60
自引率
0.00%
发文量
24
审稿时长
101 days
期刊介绍: To provide to national and regional audiences experiences unique to them or confirming of broader concepts originating in large controlled trials. All aspects of organ, tissue and cell transplantation clinically and experimentally. Transplantation Reports will provide in-depth representation of emerging preclinical, impactful and clinical experiences. -Original basic or clinical science articles that represent initial limited experiences as preliminary reports. -Clinical trials of therapies previously well documented in large trials but now tested in limited, special, ethnic or clinically unique patient populations. -Case studies that confirm prior reports but have occurred in patients displaying unique clinical characteristics such as ethnicities or rarely associated co-morbidities. Transplantation Reports offers these benefits: -Fast and fair peer review -Rapid, article-based publication -Unrivalled visibility and exposure for your research -Immediate, free and permanent access to your paper on Science Direct -Immediately citable using the article DOI
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