慢性肾衰竭患者与生活质量的药物亲和力关系,伴有高血压和血液透析

Hubungan Kepatuhan, Pengobatan Dengan, Kualitas Hidup, Pasien Gagal, Ginjal Kronik, Disertai Hipertensi, dan Menjalani Hemodialisis, Agustina Nila Yuliawati, Pande Made, Desyana Ratnasari, Gusti Ayu, Santhi Pratiwi
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引用次数: 1

摘要

接受血液透析(HD)的终末期肾病(ESRD)患者可能会遇到一些问题,从而降低他们的生活质量(QOL)。药物依从性(MA),包括HD对改善患者的生活质量非常重要。本研究旨在分析ESRD患者MA与生活质量的相关性及其相关因素。这项横断面研究于2020年9月在巴厘岛布莱伦的一家公立医院进行。通过有目的的抽样技术获得了89人的样本。本研究的纳入标准为年龄≥18岁、接受HD、完整填写问卷并能够良好沟通的ESRD患者。使用ERSD-AQ和EQ-5D-5L问卷以及药物记录收集数据。数据分析采用Perason秩相关、Spearman rho、Kendall tau-b/c、Mann-Whitney U或Kruskal-Wallis检验(CI 95%)。调查结果显示,大多数受访者为0.05)。否则,年龄<60岁、受教育程度和收入水平高以及接受药物项目数量多的患者往往有更好的生活质量(p<0.05)。
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Hubungan Kepatuhan Pengobatan Dengan Kualitas Hidup Pasien Gagal Ginjal Kronik Disertai Hipertensi dan Menjalani Hemodialisis
End-stage renal disease (ESRD) patients undergoing hemodialysis (HD) could experience several problems, then reducing their quality of life (QOL). Medication adherence (MA), including HD is very important to improve the patient's QOL. This study aimed to analyze the correlation between MA and QOL and its related factors in ESRD patients. This cross-sectional study was conducted at a Public Hospital, Buleleng, Bali in September 2020. A sample of 89 people was obtained by the purposive sampling technique. The inclusion criteria for this study were ESRD patients aged ≥18 years, undergoing HD, filling out the questionnaire completely, and being able to communicate well. Data were collected using ERSD-AQ and EQ-5D-5L questionnaire, also medication records. Data analysis were performed by Perason’s rank correlation, Spearman’s rho, Kendall’s tau-b/c, Mann-Whitney U, or Kruskal Wallis test (CI 95%). Findings showed that mostly respondents were <60 years old (66.3%), male (71.9%), less than high school educational (68.5%), not working (69.7%), lower income (55.1%), having an ESRD duration of <3 years (67.4%), taking ≤6 item medicines (96.6%), having a mean (±SD) QOL-based on a utility value of 0.779±0.172 and a visual analog scale (VAS) of 60.79±18.04. Hence, there was no significant correlation between MA and QOL, as well as patient characteristics to MA (p>0.05).). Otherwise, patients aged <60 years, high levels of education and income, as well as the number of drug items received, tend to have a better QOL (p<0.05).
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