{"title":"基于深度学习分类和多模态合成的脑磁共振图像分割","authors":"R. Kala, P. Deepa","doi":"10.2174/1574362414666181220105908","DOIUrl":null,"url":null,"abstract":"\n\nAccurate detection of brain tumor and its severity is a challenging task in\nthe medical field. So there is a need for developing brain tumor detecting algorithms and it is an\nemerging one for diagnosis, planning the treatment and outcome evaluation.\n\n\n\nBrain tumor segmentation method using deep learning classification and\nmulti-modal composition has been developed using the deep convolutional neural networks. The\ndifferent modalities of MRI such as T1, flair, T1C and T2 are given as input for the proposed\nmethod. The MR images from the different modalities are used in proportion to the information\ncontents in the particular modality. The weights for the different modalities are calculated blockwise\nand the standard deviation of the block is taken as a proxy for the information content of the\nblock. Then the convolution is performed between the input image of the T1, flair, T1C and T2\nMR images and corresponding to the weight of the T1, flair, T1C, and T2 images. The convolution\nis summed between the different modalities of the MR images and its corresponding weight\nof the different modalities of the MR images to obtain a new composite image which is given as\nan input image to the deep convolutional neural network. The deep convolutional neural network\nperforms segmentation through the different layers of CNN and different filter operations are performed\nin each layer to obtain the enhanced classification and segmented spatial consistency results.\nThe analysis of the proposed method shows that the discriminatory information from the different\nmodalities is effectively combined to increase the overall accuracy of segmentation.\n\n\n\nThe proposed deep convolutional neural network for brain tumor segmentation method\nhas been analysed by using the Brain Tumor Segmentation Challenge 2013 database (BRATS\n2013). The complete, core and enhancing regions are validated with Dice Similarity Coefficient\nand Jaccard similarity index metric for the Challenge, Leaderboard, and Synthetic data set. To\nevaluate the classification rates, the metrics such as accuracy, precision, sensitivity, specificity,\nunder-segmentation, incorrect segmentation and over segmentation also evaluated and compared\nwith the existing methods. Experimental results exhibit a higher degree of precision in the segmentation\ncompared to existing methods.\n\n\n\n In this work, deep convolution neural network with different modalities of MR image\nare used to detect the brain tumor. The new input image was created by convoluting the input\nimage of the different modalities and their weights. The weights are determined using the standard\ndeviation of the block. Segmentation accuracy is high with efficient appearance and spatial consistency.\nThe assessment of segmented images is completely evaluated by using well-established\nmetrics. In future, the proposed method will be considered and evaluated with other databases and\nthe segmentation accuracy results should be analysed with the presence of different kind of noises.\n","PeriodicalId":10868,"journal":{"name":"Current Signal Transduction Therapy","volume":"15 1","pages":"94-108"},"PeriodicalIF":0.0000,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1574362414666181220105908","citationCount":"0","resultStr":"{\"title\":\"Segmentation of Brain Magnetic Resonance Images using Deep Learning Classification and Multi-modal Composition\",\"authors\":\"R. Kala, P. Deepa\",\"doi\":\"10.2174/1574362414666181220105908\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n\\nAccurate detection of brain tumor and its severity is a challenging task in\\nthe medical field. So there is a need for developing brain tumor detecting algorithms and it is an\\nemerging one for diagnosis, planning the treatment and outcome evaluation.\\n\\n\\n\\nBrain tumor segmentation method using deep learning classification and\\nmulti-modal composition has been developed using the deep convolutional neural networks. The\\ndifferent modalities of MRI such as T1, flair, T1C and T2 are given as input for the proposed\\nmethod. The MR images from the different modalities are used in proportion to the information\\ncontents in the particular modality. The weights for the different modalities are calculated blockwise\\nand the standard deviation of the block is taken as a proxy for the information content of the\\nblock. Then the convolution is performed between the input image of the T1, flair, T1C and T2\\nMR images and corresponding to the weight of the T1, flair, T1C, and T2 images. The convolution\\nis summed between the different modalities of the MR images and its corresponding weight\\nof the different modalities of the MR images to obtain a new composite image which is given as\\nan input image to the deep convolutional neural network. The deep convolutional neural network\\nperforms segmentation through the different layers of CNN and different filter operations are performed\\nin each layer to obtain the enhanced classification and segmented spatial consistency results.\\nThe analysis of the proposed method shows that the discriminatory information from the different\\nmodalities is effectively combined to increase the overall accuracy of segmentation.\\n\\n\\n\\nThe proposed deep convolutional neural network for brain tumor segmentation method\\nhas been analysed by using the Brain Tumor Segmentation Challenge 2013 database (BRATS\\n2013). The complete, core and enhancing regions are validated with Dice Similarity Coefficient\\nand Jaccard similarity index metric for the Challenge, Leaderboard, and Synthetic data set. To\\nevaluate the classification rates, the metrics such as accuracy, precision, sensitivity, specificity,\\nunder-segmentation, incorrect segmentation and over segmentation also evaluated and compared\\nwith the existing methods. Experimental results exhibit a higher degree of precision in the segmentation\\ncompared to existing methods.\\n\\n\\n\\n In this work, deep convolution neural network with different modalities of MR image\\nare used to detect the brain tumor. The new input image was created by convoluting the input\\nimage of the different modalities and their weights. The weights are determined using the standard\\ndeviation of the block. Segmentation accuracy is high with efficient appearance and spatial consistency.\\nThe assessment of segmented images is completely evaluated by using well-established\\nmetrics. In future, the proposed method will be considered and evaluated with other databases and\\nthe segmentation accuracy results should be analysed with the presence of different kind of noises.\\n\",\"PeriodicalId\":10868,\"journal\":{\"name\":\"Current Signal Transduction Therapy\",\"volume\":\"15 1\",\"pages\":\"94-108\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.2174/1574362414666181220105908\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Signal Transduction Therapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1574362414666181220105908\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Signal Transduction Therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1574362414666181220105908","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Segmentation of Brain Magnetic Resonance Images using Deep Learning Classification and Multi-modal Composition
Accurate detection of brain tumor and its severity is a challenging task in
the medical field. So there is a need for developing brain tumor detecting algorithms and it is an
emerging one for diagnosis, planning the treatment and outcome evaluation.
Brain tumor segmentation method using deep learning classification and
multi-modal composition has been developed using the deep convolutional neural networks. The
different modalities of MRI such as T1, flair, T1C and T2 are given as input for the proposed
method. The MR images from the different modalities are used in proportion to the information
contents in the particular modality. The weights for the different modalities are calculated blockwise
and the standard deviation of the block is taken as a proxy for the information content of the
block. Then the convolution is performed between the input image of the T1, flair, T1C and T2
MR images and corresponding to the weight of the T1, flair, T1C, and T2 images. The convolution
is summed between the different modalities of the MR images and its corresponding weight
of the different modalities of the MR images to obtain a new composite image which is given as
an input image to the deep convolutional neural network. The deep convolutional neural network
performs segmentation through the different layers of CNN and different filter operations are performed
in each layer to obtain the enhanced classification and segmented spatial consistency results.
The analysis of the proposed method shows that the discriminatory information from the different
modalities is effectively combined to increase the overall accuracy of segmentation.
The proposed deep convolutional neural network for brain tumor segmentation method
has been analysed by using the Brain Tumor Segmentation Challenge 2013 database (BRATS
2013). The complete, core and enhancing regions are validated with Dice Similarity Coefficient
and Jaccard similarity index metric for the Challenge, Leaderboard, and Synthetic data set. To
evaluate the classification rates, the metrics such as accuracy, precision, sensitivity, specificity,
under-segmentation, incorrect segmentation and over segmentation also evaluated and compared
with the existing methods. Experimental results exhibit a higher degree of precision in the segmentation
compared to existing methods.
In this work, deep convolution neural network with different modalities of MR image
are used to detect the brain tumor. The new input image was created by convoluting the input
image of the different modalities and their weights. The weights are determined using the standard
deviation of the block. Segmentation accuracy is high with efficient appearance and spatial consistency.
The assessment of segmented images is completely evaluated by using well-established
metrics. In future, the proposed method will be considered and evaluated with other databases and
the segmentation accuracy results should be analysed with the presence of different kind of noises.
期刊介绍:
In recent years a breakthrough has occurred in our understanding of the molecular pathomechanisms of human diseases whereby most of our diseases are related to intra and intercellular communication disorders. The concept of signal transduction therapy has got into the front line of modern drug research, and a multidisciplinary approach is being used to identify and treat signaling disorders.
The journal publishes timely in-depth reviews, research article and drug clinical trial studies in the field of signal transduction therapy. Thematic issues are also published to cover selected areas of signal transduction therapy. Coverage of the field includes genomics, proteomics, medicinal chemistry and the relevant diseases involved in signaling e.g. cancer, neurodegenerative and inflammatory diseases. Current Signal Transduction Therapy is an essential journal for all involved in drug design and discovery.