硼中子俘获治疗(BNCT)转化研究的教学:“跳出框框”思考

A. Schwint, M. A. Garabalino, A. M. Hughes, E. C. Pozzi, E. Heber, M. Palmieri, V. Trivillin
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引用次数: 5

摘要

BNCT是一种治疗实体瘤的技术。BNCT被认为是一种二元技术,因为它涉及两个单独发挥很少或没有作用的成分,但当它们结合在一起时会产生显著影响。BNCT是基于中子照射和10种B化合物的给药的组合,这些化合物通过不同的机制选择性地被肿瘤组织掺入,这取决于硼载体。
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Teachings of our translational studies on boron neutron capture therapy (BNCT): thinking “outside the box”
BNCT is a technique for the treatment of solid tumors. BNCT is considered a binary technique because it involves two components that exert little or no action individually but induce a significant effect when they combine. BNCT is based on the combination of neutron irradiation and the administration of 10 B compounds that are incorporated selectively by tumor tissue via different mechanisms, depending on the boron carrier.
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