Recurrent lymphoma as a cause of obscure massive small bowel bleeding

Diffuse large B-cell lymphoma (DLBCL) is an aggressive malignancy that accounts for the largest proportion of non-Hodgkin lymphoma. The gastrointestinal (GI) tract is the most common site of extra-nodal involvement.1,2 Subsequent gastrointestinal bleeding can be a life-threatening complication. Recurrent lymphoma is unusual to present with gastrointestinal hemorrhage, especially after longstanding remission. Here, we present obscure massive small bowel bleeding as the initial presentation of recurrent DLBCL.