青年高危神经母细胞瘤与多模式治疗的长期生存:一例报告

A. Oehadian, Afiati Afiati, Martina Sung, Kevin Yonatan Budiman, F. Fransisca
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引用次数: 0

摘要

目的:报告一例高危的4期神经母细胞瘤,患者为一名20岁女性,经多模式治疗后存活超过21个月。方法:报告一例高危的4期神经母细胞瘤患者,该患者为一名20岁女性,通过多模式治疗存活了21个月以上。根据土耳其神经母细胞瘤儿科肿瘤学小组的说法,该患者最初接受了新辅助化疗,并接受了多剂量放疗。经过两个周期的诱导化疗,她成功地接受了肿瘤切除手术。结果:采用多模式治疗,患者仍处于完全缓解状态,其余病变病情稳定。结论:神经母细胞瘤是一种罕见的成人疾病,死亡率高。早期准确的诊断和多种治疗方式对实现疾病控制至关重要。对此类患者进行长期随访是必要的。
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High-risk Neuroblastoma in Young Adult and Long Term Survival with Multimodal Therapy: A Case Report
Objective: To present a case of high-risk, stage four neuroblastoma in a 20-year-old woman who survived more than 21 months with the multimodal therapy.Methods: A case of high-risk, stage four neuroblastoma in a 20-year-old woman who survived more than 21 months with multimodal therapy is reported. The patient initially received neoadjuvant chemotherapy according to the Turkish Pediatric Oncology Group of Neuroblastoma, along with multiple doses of radiotherapy. After two cycles of induction chemotherapy, she successfully underwent tumor debulking surgery.Results: With the multimodal therapy, patient remains in complete remission state and stable disease of the remaining lesions is observed in this patient.Conclusions: Neuroblastoma is a rare disease in adults and associated with a high number of mortality. Early and accurate diagnosis and multimodality of treatments are important to achieve disease control. Long term follow up is necessary for such patients.
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