一例具有免疫功能的儿童患者的鼻腔眼眶毛霉菌病,类似眼眶肿块-病例报告

S. M. Rafizadeh, M. Aminizade, F. A. Amoli, M. Anari, M. Khodabandeh, Abbas Mohammadi
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摘要

鼻-眼眶毛霉菌病在免疫功能正常的儿科患者可以表现为眼眶肿块。我们报告一个9岁的男性,从一个月前出现眼眶周围肿胀和左眼运动受限。患者曾在另一中心治疗,诊断为毛霉病,但因症状恶化而转诊。眼眶及鼻窦CT显示左侧鼻窦混浊,眶内及下壁软组织密度大。病人因怀疑可能有肿瘤肿块而接受眼窝切开及肿块减积手术。病理检查显示为毛霉病。经静脉滴注两性霉素- b脂质体,口服泊沙康唑糖浆2个月,鼻窦清创后症状消退。在免疫功能低下的儿童患者中,在眼眶肿块的鉴别诊断中应考虑毛霉菌病。
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Rhino-orbital Mucormycosis in an Immunocompetent Pediatric Patient, Resembling an Orbital Mass- a Case Report
Rhino-orbital mucormycosis in an immunocompetent pediatric patient can present as an orbital mass. We report a 9-year-old male that presented with periorbital swelling and limitation of left eye movement from one month ago. The patient was treated at another center with a diagnosis of mucormycosis but was referred due to worsening symptoms. Orbital and paranasal sinus CT scan revealed opacities in the left paranasal sinus and soft tissue density in the medial and inferior orbital wall. The patient underwent orbitotomy and mass debulking surgery on suspicion of a possible neoplastic mass. Pathologic evaluations revealed mucormycosis. After receiving intravenous liposomal amphotericin-B that was followed by oral posaconazole syrup for two months and sinus debridement, the symptoms regressed. In immunocompromised pediatric patients, mucormycosis should be considered in the differential diagnosis of an orbital mass.
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