噬菌体展示——一种检测和预防病原体的工具。综述

Q4 Agricultural and Biological Sciences Nova Biotechnologica et Chimica Pub Date : 2021-12-04 DOI:10.36547/nbc.1304
B. Vidová, A. Godány
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引用次数: 0

摘要

本文综述了噬菌体展示在微生物病原体检测和疫苗接种等领域的应用前景。噬菌体展示是一种在噬菌体颗粒表面表达外源蛋白质的分子技术。这样的噬菌体因此成为表达载体,其内不仅携带编码表达蛋白质的核苷酸序列,而且具有复制能力。从基因组测序和噬菌体生物学研究进展中获得的最新数据有助于噬菌体衍生细菌检测和治疗策略的发展。
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Phage display – a tool for detection and prevention against pathogens. A review
In this article are reviewed the promising uses of phage display in the areas such as microbial pathogens detection of and vaccination. Phage display is a molecular technique by which foreign proteins are expressed at the surface of phage particles. Such phages thereby become vehicles for expression that not only carry within them the nucleotide sequence encoding expressed proteins, but have also the capability to replicate. Recent data acquired from genome sequencing and advances in phage biology research have aided the development of phage-derived bacterial detection and treatment strategies.
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来源期刊
Nova Biotechnologica et Chimica
Nova Biotechnologica et Chimica Agricultural and Biological Sciences-Food Science
CiteScore
0.60
自引率
0.00%
发文量
47
审稿时长
24 weeks
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