本月医学图像:肝移植后患者与covid -19相关的肺曲霉病

P. Anandajith, Z. Mohamed, D. Balakrishnan, S. Sudhindran
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没有可用的摘要。文章前150字后被截断。一名先前健康的48岁女性,因自身免疫性病因继发的急慢性肝功能衰竭(III级)而入院,在常规入院筛查中被发现为严重急性呼吸系统综合征冠状病毒2型RTPCR阳性。她最初接受了标准的新冠肺炎医疗护理,包括类固醇治疗。由于脑病恶化,她需要有创通气,10天后抗原检测呈阴性,她接受了紧急肝移植。她的术前感染筛查(血液培养、支气管肺泡灌洗、尿液)为阴性,胸部计算机断层扫描(CT)正常(图1)。她在肝移植后第3天拔管。直到术后第10天,她出现咳嗽和不饱和症状,她的恢复才平静下来。重复CT胸部显示多个多叶实性结节,中心破裂累及双肺(图2)。她的支气管肺泡灌洗培养培养培养出烟曲霉(唑敏感),符合证明新冠肺炎相关肺曲霉菌病的标准…
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Medical Image of the Month: COVID-19-Associated Pulmonary Aspergillosis in a Post-Liver Transplant Patient
No abstract available. Article truncated after first 150 words. A previously healthy, 48-year-old woman, admitted with a working diagnosis of acute-on-chronic liver failure (Grade III) secondary to an autoimmune etiology, was found to be SARS COV-2 RTPCR positive on routine admission screening. She was initially managed with standard medical care for COVID, including steroids. She required invasive ventilation for worsening encephalopathy and when her antigen test was negative 10 days later, she underwent an urgent liver transplantation. Her preoperative infection screen (culture of blood, bronchoalveolar lavage, urine) was negative and computerized tomography (CT) of the chest was normal (Figure 1). She was extubated on day 3 after liver transplantation. Her recovery was uneventful until the 10th postoperative day when she developed cough and desaturation. A repeat CT chest showed multiple multilobular consolidatory nodules with central breakdown involving both lung (Figure 2). Her bronchoalveolar lavage culture grew Aspergillus fumigatus (azole sensitive) which fulfilled criteria for proven COVID-19 Associated pulmonary aspergillosis …
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