在成年癫痫患者中使用补充和替代药物——马来西亚一家癫痫中心的经验

Q4 Neuroscience Neuroscience Research Notes Pub Date : 2022-02-07 DOI:10.31117/neuroscirn.v5i1.109
M. Koh, S. Khor, K. Lim, Si-Lei Fong, Wei-Zhen Low, Li-Ling Yeap, C. Tan
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引用次数: 1

摘要

欧洲、美利坚合众国和亚洲单民族国家如韩国和台湾报告了补充和替代药物(CAM)的使用。然而,在多种族国家,特别是马来西亚,关于癫痫患者CAM使用模式的可变性的文献有限。这项横断面研究评估了成年PWE患者CAM使用的患病率、类型、预测因素和影响,以及他们对抗癫痫药物(AED)治疗的依从性。共招募了140名患者,中位年龄为37.5岁(IQR,28.0-51.5),大多数为女性,具有中等或更低的教育水平,收入<1077美元,每月癫痫发作频率<1次。四分之一(25.7%)的患者使用CAM控制癫痫发作,其中94.4%的患者在使用CAM时坚持AED治疗。常用的CAM有祈祷、传统草药、按摩和针灸。只有33.3%的人与医生讨论过CAM的使用。CAM使用的主要原因是患者愿意尝试其他替代品来控制癫痫发作。尽管大多数患者没有使用CAM,但20.2%的患者接受使用CAM作为联合治疗。佛教徒对CAM更开放,而穆斯林则选择性地使用CAM,避免使用护身符、针灸、脊椎按摩、阿育吠陀、瑜伽和灵气。Logistic回归分析显示,佛教(OR,11.01)、穆斯林(OR,4.04)、每月癫痫发作≥1次(OR,3.85)和月收入≥1077美元(OR,2.92)是CMA使用的预测因素。CAM的使用在马来西亚很常见,尤其是在社会经济地位较高、癫痫发作失控的佛教徒和穆斯林中。CAM主要用于补充AED,但不用于替代AED。
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Use of complementary and alternative medicine among adult with epilepsy - experiences from a single epilepsy center in Malaysia
Complementary and alternative medicine (CAM) usage were reported in Europe, the United States of America and monoethnic Asian countries such as Korea and Taiwan. However, limited literature is available on the variability of CAM usage patterns among people with epilepsy (PWE) in a multi-racial country in particular Malaysia. This cross-sectional study assessed the prevalence, types, predictors and impact of CAM use among adult PWE and their adherence to anti-epileptic drugs (AEDs) treatment.140 patients were recruited, with a median age of 37.5 (IQR,28.0-51.5) years, majority female, had secondary or lower education level, earn
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