高海拔人群肝硬化的临床特征及并发症(万卡约,3250 m s.n. m.)

Walter Calderón Gerstein, Maritza Ascanio Paredes, Pilar Rocío Yarinsueca Mata
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引用次数: 0

摘要

目的:肝硬化是重要的发病率和死亡率。本研究旨在确定秘鲁高海拔地区肝硬化患者的临床表现、病因学和并发症。材料与方法:对肝硬化的临床表现及并发症进行回顾性研究。在2010年至2012年期间,对万卡约国立Ramiro Priale Priale医院内科收治的108例肝硬化患者的病历进行了评估。结果:患者平均年龄60.5岁(范围12 ~ 82岁),男性占62.9%。最常见的病因是饮酒(63%),其次是慢性乙型肝炎和丙型肝炎(分别为7.4%和2.8%)。58.3%的患者Child-Pugh评分为B级,31.30%的患者Child-Pugh评分为C级。最常见的临床表现是腹胀(87%)。最常见的并发症是腹水(56%)、肝性脑病(47.2%)和肝肾综合征(8.3%)。结论:酒精性肝硬化是最常见的病因。最常见的并发症是腹水和肝性脑病
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Características clínicas y complicaciones de la cirrosis hepática en una población de altura (Huancayo, 3250 m s. n. m.)
Objective: Liver cirrhosis is responsible for significant morbidity and mortality. This research aims to determine the clinical presentation, etiology and complications of patients with liver cirrhosis from a population living at a high altitude region in Peru. Materials and methods: A retrospective study of the clinical presentation and complications of liver cirrhosis was conducted. One hundred eight (108) medical records of patients with liver cirrhosis admitted to the Internal Medicine Service of the Hospital Nacional Ramiro Priale Priale, Huancayo,were evaluated between 2010 and 2012. Results: Patients’ mean age was 60.5 years (range: 12–82 years) and 62.9 % were males. The most common etiology was alcohol consumption (63 %), followed by chronic hepatitis B and C (7.4 % and 2.8 %, respectively). Fifty-eight point three percent (58.3 %) of the patients had a Child-Pugh class B score and 31.30 % of them had a Child-Pugh class C score. The most frequent clinical presentation was abdominal distension (87 %). The most common complications were ascites (56 %), hepatic encephalopathy (47.2 %) and hepatorenal syndrome (8.3 %). Conclusions: Alcoholic liver cirrhosis was the most common etiology. The most frequent complications were ascites and hepatic encephalopathy
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