京津冀城市群ICU VAE预防措施现状调查与分析

Longfei Kang, Okada Shinobu, Ogawa Toshiko
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引用次数: 0

摘要

患肺炎的风险。苯二氮卓类药物和异丙酚与VAE风险增加有关,但右美托咪定与此无关。3)低潮气量通气(LTVV):多项研究表明,低潮气量通气可减少非ARDS患者的ARDS、肺不张和肺部感染[13-15]。4)维持胃酸:MV患者预防性使用抗溃疡药,预防应激性溃疡。抗溃疡剂引起的胃液pH值升高已被证明可促进胃内致病菌的增殖。这些细菌的吸入被认为是VAP的原因之一。研究表明,与质子泵抑制剂和H2受体阻滞剂[16]相比,使用不影响胃酸的抗溃疡药(如硫硫钠)的VAP发生率较低。
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Investigation and Analysis of the Current Situation of VAE Preventive Measures in ICU in Beijing-Tianjin-Hebei Urban Agglomeration of China
of developing pneumonia. Benzodiazepines and propofol were associated with an increased VAE risk, but not dexmedetomidine [12]. 3) Low tidal volume ventilation (LTVV): Several studies have shown that low tidal volume MV reduce ARDS, atelectasis, and lung infections in patients without ARDS [13-15]. 4) Maintenance of gastric acid: Anti-ulcerative agents are prophylactically administered in MV patients to prevent stress ulcers. The increased pH of gastric juice caused by anti-ulcerative agents has been shown to promote proliferation of pathogenic bacteria in the stomach. Aspiration of these bacteria is considered as one of the causes of VAP. Studies have shown that administration of anti-ulcerative agents that did not affect gastric acidity, such as sucralfate had a lower incidence of VAP, compared to proton pump inhibitors and H2 receptor blockers [16].
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