关于记录药物溶解度测量方法的重要性的评论，包括描述溶质的物理形式，以有意义地理解、解释和报告溶解度数据

IF 1 4区医学 Q4 PHARMACOLOGY & PHARMACY Dissolution Technologies Pub Date : 2019-11-01 DOI:10.14227/dt260419p6

W. Brown, V. Gray, J. Krämer, J. Mauger, K. Warner

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引用次数: 1

摘要

这篇评论继续了前一篇题为“对溶出科学与技术中数据透明度、开放性和可重复性的重要性的评论”的讨论(1)。作为后续，这篇评论更具体地提供了适用于溶出技术中报告的溶解度数据的文献中当前实践的扫描，目的是提高这些数据的可重复性和有意义的解释。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Comment on the Importance of Documenting Drug Solubility Measurement Methodology, Including Characterizing the Physical Form of the Solute, for Meaningful Understanding, Interpretation, and Reporting of Solubility Data

T his commentary continues the discussion initiated in a previous article entitled “Comment on the Importance of Data Transparency, Openness, and Reproducibility in Dissolution Science and Technology” (1). As a follow-up, this commentary more specifically provides a scan of current practices in the literature that are applicable to solubility data reported in Dissolution Technologies, with the goal of enhancing reproducibility and meaningful interpretations of these data.

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来源期刊

Dissolution Technologies 医学-药学

CiteScore

1.20

自引率

33.30%

发文量

审稿时长

3 months

期刊介绍： Dissolution Technologies is a peer reviewed quarterly publication reporting ongoing, useful information on dissolution testing of pharmaceuticals. It provides an international forum for dissolution analysts to receive and exchange information on various dissolution topics. Dissolution Technologies welcomes submissions related to dissolution, in vitro release, and disintegration testing. These topics should be the major focus of the article. Do not submit articles where the focus is formulation development with dissolution testing as one of many tests.