三级甲等医院门诊处方对感染治疗实践的调查

S. Shyam, S. Jaiswal, A. Jayabalan, S. Shergill
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摘要

简介:印度是世界上最大的抗生素消费国。抗菌剂(AMA)也是滥用最多和处方过多的治疗剂。目的:对一家三级护理政府医院的门诊部(OPD)处方单进行调查,以描述当前感染管理的治疗实践。受试者和方法:分析了一千五百张门诊处方,以了解每个专业门诊处方的抗菌药物的流行率以及使用这些AMA治疗的系统性感染。获得了2018年的抗生素敏感性测试数据,用于分析当前医院感染的治疗实践。结果:在医院七个科室的1500张门诊处方中,约24.4%含有抗菌药物。AMA的比例最高的是牙科门诊(66.6%),其次是耳鼻喉科和外科门诊(分别为36.8%和36%),而AMA的处方最少的是妇科和产科门诊(11%)。在367张AMA处方中,有92张处方含有2种或2种以上抗菌药物。处方中约54.7%是非专利口服药物,只有两个处方是注射型AMA。62%的AMA处方的使用时间在5到10天之间。根据世界卫生组织分类,53.4%的AMA处方计数属于抗生素ACCESS组,44.1%属于WATCH组,2.5%属于RESERVE组。结论:本研究强调有必要根据医院抗生素敏感性测试,重新制定门诊患者抗菌药物使用的当地指南。
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A survey of out patient department prescriptions of selected departments of a tertiary care hospital on treatment practices of infections
Introduction: India is the largest consumer of antibiotics in the world. Antimicrobial agents (AMA) are also the most misused and excessively prescribed therapeutic agents. Objectives: A survey of output patient department (OPD) prescription chits of a tertiary care government hospital was carried out to describe the current treatment practices in the management of infections. Subjects and Methods: Thousand and five hundred OPD prescriptions were analyzed for the prevalence of antimicrobials prescribed by each specialist OPD and the systemic infections which were treated by using these AMA. The data of antibiotic susceptibility tests for the year 2018 were obtained for the analysis on current treatment practices of hospital infections. Results: About 24.4% of all 1500 OPD prescriptions encountered from the seven departments of the hospital contained an antibacterial. The highest proportion of AMA was seen in the dental OPD (66.6%) followed by ENT and surgical OPD (36.8% and 36%, respectively) and the least AMA were prescribed in gynecology and obstetrical OPD (11%). Out of the 367 AMA prescriptions, 92 prescriptions had 2 or more antibacterials. About 54.7% of these AMA prescribed were generic oral drugs and only two prescription counts were of injectable AMA. 62% of the AMA prescriptions were for the duration of use between 5 and 10 days. 53.4% of the AMA prescription counts belonged to the ACCESS group of antibiotics, 44.1% to the WATCH group and 2.5% to the RESERVE group as classified by WHO. Conclusions: The present study emphasizes the need to re-formulate local guidelines of antimicrobial use in OPD patients based on hospital antibiotic susceptibility tests.
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