{"title":"病原微生物核酸检测的研究进展。(特刊:生物安全材料)","authors":"Liu Zi-yue, Yang Tong-Ren, Y. Ge, Huang Yuanyu","doi":"10.19894/J.ISSN.1000-0518.210099","DOIUrl":null,"url":null,"abstract":"In December 2019, the global outbreak of Corona Virus Disease 2019 (COVID-19)made biosafety an attractive and crucial development direction globally. Rapid, accurate and low-cost detection of pathogenic microorganisms is one of the important issue to ensure biosafety, and is the key to epidemic prevention, control and diagnosis. This review elaborately introduces the applications of biosensors based on nucleic acid sequencing, isothermal amplification and gene editing (CRISPR/Cas) in integrated portable devices. The development of these technologies offers the possibility of developing low-cost, high-efficiency and result-visualization integrated detection methods. It is expected to provide technology guarantees for the effective prevention and control of pathogenic microorganisms.","PeriodicalId":9936,"journal":{"name":"应用化学","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Research progresses of nucleic acid based detection of pathogenic microorganisms. (Special Issue: Biosafety materials.) [Chinese]\",\"authors\":\"Liu Zi-yue, Yang Tong-Ren, Y. Ge, Huang Yuanyu\",\"doi\":\"10.19894/J.ISSN.1000-0518.210099\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In December 2019, the global outbreak of Corona Virus Disease 2019 (COVID-19)made biosafety an attractive and crucial development direction globally. Rapid, accurate and low-cost detection of pathogenic microorganisms is one of the important issue to ensure biosafety, and is the key to epidemic prevention, control and diagnosis. This review elaborately introduces the applications of biosensors based on nucleic acid sequencing, isothermal amplification and gene editing (CRISPR/Cas) in integrated portable devices. The development of these technologies offers the possibility of developing low-cost, high-efficiency and result-visualization integrated detection methods. It is expected to provide technology guarantees for the effective prevention and control of pathogenic microorganisms.\",\"PeriodicalId\":9936,\"journal\":{\"name\":\"应用化学\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"应用化学\",\"FirstCategoryId\":\"1087\",\"ListUrlMain\":\"https://doi.org/10.19894/J.ISSN.1000-0518.210099\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"应用化学","FirstCategoryId":"1087","ListUrlMain":"https://doi.org/10.19894/J.ISSN.1000-0518.210099","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Research progresses of nucleic acid based detection of pathogenic microorganisms. (Special Issue: Biosafety materials.) [Chinese]
In December 2019, the global outbreak of Corona Virus Disease 2019 (COVID-19)made biosafety an attractive and crucial development direction globally. Rapid, accurate and low-cost detection of pathogenic microorganisms is one of the important issue to ensure biosafety, and is the key to epidemic prevention, control and diagnosis. This review elaborately introduces the applications of biosensors based on nucleic acid sequencing, isothermal amplification and gene editing (CRISPR/Cas) in integrated portable devices. The development of these technologies offers the possibility of developing low-cost, high-efficiency and result-visualization integrated detection methods. It is expected to provide technology guarantees for the effective prevention and control of pathogenic microorganisms.