微塑料塑造了人类胃肠道的生态

IF 6.1 Q1 TOXICOLOGY Current Opinion in Toxicology Pub Date : 2021-12-01 DOI:10.1016/j.cotox.2021.09.006
Silvia Turroni , Stephanie Wright , Simone Rampelli , Patrizia Brigidi , Pier Luigi Zinzani , Marco Candela
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引用次数: 2

摘要

塑料微粒是全球性的污染物,在饮用水、灰尘和一些食品中都有检测到。对人口接触和由此对人类健康造成的风险的关切日益增加。由于肠道可以被认为是人体微塑料暴露的主要部位之一,在这里,我们探讨了摄入的微塑料颗粒对胃肠道生态的可能影响,为它们作为人类肠道微生物群中生态失调变化的驱动因素提供了一些证据。这进一步强调,迫切需要定量评估人体肠道中微塑料的口服暴露和危害,从而推断出微塑料风险水平和肠道微生物群中生态失调变化的结果。
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Microplastics shape the ecology of the human gastrointestinal intestinal tract

Microplastic particles are global pollutants which have been measured in drinking water, dust, and some food items. Concerns about population exposures and the resulting risks to human health are increasing. Because the gut can be considered one of the primary sites for microplastic exposure in the human body, here, we explore the possible impact of ingested microplastic particles on gastrointestinal ecology, providing some evidence for their active role as a driver of dysbiotic variation in the human gut microbiome. This further stresses the urgent need to quantitatively assess both oral exposure and hazards of microplastic in the human gut, enabling prediction of the levels of microplastic risk and outcomes of dysbiotic changes in the gut microbiome to be inferred.

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来源期刊
Current Opinion in Toxicology
Current Opinion in Toxicology Pharmacology, Toxicology and Pharmaceutics-Toxicology
CiteScore
10.40
自引率
0.00%
发文量
43
期刊介绍: The aims and scope of Current Opinion in Toxicology is to systematically provide the reader with timely and provocative views and opinions of the highest qualified and recognized experts on current advances in selected topics within the field of toxicology. The goal is that Current Opinion in Toxicology will be an invaluable source of information and perspective for researchers, teachers, managers and administrators, policy makers and students. Division of the subject into sections: For this purpose, the scope of Toxicology is divided into six selected high impact themed sections, each of which is reviewed once a year: Mechanistic Toxicology, Metabolic Toxicology, Risk assessment in Toxicology, Genomic Toxicology, Systems Toxicology, Translational Toxicology.
期刊最新文献
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