墨西多和硝化甘油对动物肝组织一氧化氮形成的联合作用

T. Zhumabaeva, Z. Kuropteva, Zh. T. Moldaliev, Nazgul Zhumabaeva, A. Kadyrbaeva, Nurbek Bopoev, Z. Abdullaeva
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引用次数: 0

摘要

Mexidol(2-乙基-6-甲基-3-羟基琥珀酸吡啶)对动物肝脏组织一氧化氮(NO)形成的影响,一氧化氮是许多生理过程的调节剂,在血管舒张、神经传递和免疫系统功能中起重要作用。EPR光谱分析显示任意单位的顺磁中心有Hem-NO复合信号;采用亚硝基配合物双积分信号法测定肝脏组织中产生的氮氧化物量。
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Joint Effects of Mexidol and Nitroglycerine on Nitric Oxide Formation in Animal Liver Tissues
This work is investigating Mexidol (2-ethyl-6-methyl-3-hydroxy pyridine succinate) effect on the formation of nitric oxide (NO) in animal liver tissues, which is a regulator of many physiological processes and plays an important role in the vascular relaxation, neurotransmission and immune system functioning. Analyses performed by EPR spectroscopy revealed Hem-NO complex signals from paramagnetic centers in arbitrary units; produced nitrogen oxide amount in liver tissues was determined by method of double integration signals from nitrosyl complexes.
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