经皮冠状动脉介入治疗老年非ST段抬高型心肌梗死患者C反应蛋白/白蛋白比值与住院死亡率的关系

IF 0.4 4区 医学 Q4 GERIATRICS & GERONTOLOGY Turkish Journal of Geriatrics-Turk Geriatri Dergisi Pub Date : 2023-03-01 DOI:10.29400/tjgeri.2023.326
Oğuz Kılıç, Fatma Özpamuk Karadeniz, F. Kahraman
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引用次数: 0

摘要

引言:急性心肌梗死是世界范围内最常见的心血管疾病,也是造成重大死亡的原因。衡量炎症状况的C反应蛋白/白蛋白比率可用于预测死亡率。在本研究中,我们旨在调查在我院接受介入治疗的非ST段抬高型心肌梗死患者的住院死亡率与C反应蛋白/白蛋白比率之间的关系。材料与方法:研究对象为297名老年患者。患者的信息是从医院数据库中获得的。计算每位患者的C反应蛋白/白蛋白比率。我们使用回归分析来研究C反应蛋白/白蛋白比率与住院死亡率之间的关系。结果:单变量分析显示,性别、射血分数、白细胞、葡萄糖、肌酸酐、收缩压和舒张压、心率、GRACE风险评分和CAR比率是死亡率的重要预测因素(表2)。将所有参数添加到多变量logistic回归中,多变量逻辑回归分析显示,GRACE风险评分(OR:0.956,95%CI:0.941-0.971;p<0.001)和C反应蛋白/白蛋白比率(OR:0.812,95%CI:0.661-0.998;p=0.048)是死亡率的唯一显著预测因素。此外,双变量相关分析显示,GRACE风险评分与C反应蛋白/白蛋白比值之间存在微弱但具有统计学意义的相关性(r=0.180,p<0.001)。C反应蛋白/白蛋白比值可用于临床实践,因为它价格低廉,易于应用,对老年非ST段抬高型心肌梗死患者具有很强的预后价值。关键词:心肌梗死;白蛋白;发炎死亡率
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THE RELATIONSHIP OF THE C-REACTIVE PROTEIN /ALBUMIN RATIO TO IN-HOSPITAL MORTALITY IN ELDERLY PATIENTS WITH NON-ST-ELEVATION MYOCARDIAL INFARCTION WHO HAVE UNDERGONE PERCUTANEOUS CORONARY INTERVENTION
Introduction: Acute myocardial infarction is the most common cardiovascular disease and the cause of significant mortality worldwide. The C-reactive protein/albumin ratio, which measures inflammatory conditions, can be used to predict mortality. In this study, we aimed to investigate the relationship between in-hospital mortality and the C-reactive protein/albumin ratio in patients diagnosed with non-ST-elevation myocardial infarction who underwent interventional treatment at our hospital. Materials and Method: Two hundred and ninety-seven elderly patients were included in the study. The information of the patients was obtained from the hospital database. The C-reactive protein/albumin ratio was calculated for each patient. We used regression analysis to investigate the relationship between the C-reactive protein/albumin ratio and in-hospital mortality. Results: A univariate analysis showed that gender, ejection fraction, white blood cell, glucose, creatinine, systolic and diastolic blood pressure, heart rate, GRACE risk score, and CAR ratio were significant predictors of mortality (Table 2). All parameters were added to a multivariable logistic regression, and multivariable logistic regression analysis showed that the GRACE risk score (OR: 0.956, 95% CI: 0.941–0.971; p<0.001) and the C-reactive protein/albumin ratio (OR: 0.812, 95% CI: 0.661–0.998; p=0.048) were the only significant predictors of mortality. Furthermore, bivariate correlation analysis showed a weak but statistically significant correlation between GRACE risk score and C-reactive protein/albumin ratio (r=0.180, p<0.001). Conclusion: We found a significant relationship between C-reactive protein/albumin and in-hospital mortality. C-reactive protein/albumin ratio can be used in clinical practice because it is inexpensive and easy to apply and has a strong prognostic value for elderly non-ST-elevation myocardial infarction patients. Keywords: Myocardial Infarction; Albumin; Inflammation; Mortality.
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来源期刊
CiteScore
0.60
自引率
0.00%
发文量
46
审稿时长
6-12 weeks
期刊介绍: Turkish Journal of Geriatrics is a peer-reviewed journal. Official language of the journal is English. Turkish Journal of Geriatrics invites submission of Original Articles based on clinical and laboratory studies. Review Articles are published only after the invitation from the Editorial Board.
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