{"title":"经皮冠状动脉介入治疗老年非ST段抬高型心肌梗死患者C反应蛋白/白蛋白比值与住院死亡率的关系","authors":"Oğuz Kılıç, Fatma Özpamuk Karadeniz, F. Kahraman","doi":"10.29400/tjgeri.2023.326","DOIUrl":null,"url":null,"abstract":"Introduction: Acute myocardial infarction is the most common cardiovascular disease and the cause of significant mortality worldwide. The C-reactive protein/albumin ratio, which measures inflammatory conditions, can be used to predict mortality. In this study, we aimed to investigate the relationship between in-hospital mortality and the C-reactive protein/albumin ratio in patients diagnosed with non-ST-elevation myocardial infarction who underwent interventional treatment at our hospital. Materials and Method: Two hundred and ninety-seven elderly patients were included in the study. The information of the patients was obtained from the hospital database. The C-reactive protein/albumin ratio was calculated for each patient. We used regression analysis to investigate the relationship between the C-reactive protein/albumin ratio and in-hospital mortality. Results: A univariate analysis showed that gender, ejection fraction, white blood cell, glucose, creatinine, systolic and diastolic blood pressure, heart rate, GRACE risk score, and CAR ratio were significant predictors of mortality (Table 2). All parameters were added to a multivariable logistic regression, and multivariable logistic regression analysis showed that the GRACE risk score (OR: 0.956, 95% CI: 0.941–0.971; p<0.001) and the C-reactive protein/albumin ratio (OR: 0.812, 95% CI: 0.661–0.998; p=0.048) were the only significant predictors of mortality. Furthermore, bivariate correlation analysis showed a weak but statistically significant correlation between GRACE risk score and C-reactive protein/albumin ratio (r=0.180, p<0.001). Conclusion: We found a significant relationship between C-reactive protein/albumin and in-hospital mortality. C-reactive protein/albumin ratio can be used in clinical practice because it is inexpensive and easy to apply and has a strong prognostic value for elderly non-ST-elevation myocardial infarction patients. Keywords: Myocardial Infarction; Albumin; Inflammation; Mortality.","PeriodicalId":51196,"journal":{"name":"Turkish Journal of Geriatrics-Turk Geriatri Dergisi","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"THE RELATIONSHIP OF THE C-REACTIVE PROTEIN /ALBUMIN RATIO TO IN-HOSPITAL MORTALITY IN ELDERLY PATIENTS WITH NON-ST-ELEVATION MYOCARDIAL INFARCTION WHO HAVE UNDERGONE PERCUTANEOUS CORONARY INTERVENTION\",\"authors\":\"Oğuz Kılıç, Fatma Özpamuk Karadeniz, F. Kahraman\",\"doi\":\"10.29400/tjgeri.2023.326\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Acute myocardial infarction is the most common cardiovascular disease and the cause of significant mortality worldwide. The C-reactive protein/albumin ratio, which measures inflammatory conditions, can be used to predict mortality. In this study, we aimed to investigate the relationship between in-hospital mortality and the C-reactive protein/albumin ratio in patients diagnosed with non-ST-elevation myocardial infarction who underwent interventional treatment at our hospital. Materials and Method: Two hundred and ninety-seven elderly patients were included in the study. The information of the patients was obtained from the hospital database. The C-reactive protein/albumin ratio was calculated for each patient. We used regression analysis to investigate the relationship between the C-reactive protein/albumin ratio and in-hospital mortality. Results: A univariate analysis showed that gender, ejection fraction, white blood cell, glucose, creatinine, systolic and diastolic blood pressure, heart rate, GRACE risk score, and CAR ratio were significant predictors of mortality (Table 2). All parameters were added to a multivariable logistic regression, and multivariable logistic regression analysis showed that the GRACE risk score (OR: 0.956, 95% CI: 0.941–0.971; p<0.001) and the C-reactive protein/albumin ratio (OR: 0.812, 95% CI: 0.661–0.998; p=0.048) were the only significant predictors of mortality. Furthermore, bivariate correlation analysis showed a weak but statistically significant correlation between GRACE risk score and C-reactive protein/albumin ratio (r=0.180, p<0.001). Conclusion: We found a significant relationship between C-reactive protein/albumin and in-hospital mortality. C-reactive protein/albumin ratio can be used in clinical practice because it is inexpensive and easy to apply and has a strong prognostic value for elderly non-ST-elevation myocardial infarction patients. Keywords: Myocardial Infarction; Albumin; Inflammation; Mortality.\",\"PeriodicalId\":51196,\"journal\":{\"name\":\"Turkish Journal of Geriatrics-Turk Geriatri Dergisi\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2023-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Turkish Journal of Geriatrics-Turk Geriatri Dergisi\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.29400/tjgeri.2023.326\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"GERIATRICS & GERONTOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Turkish Journal of Geriatrics-Turk Geriatri Dergisi","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.29400/tjgeri.2023.326","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"GERIATRICS & GERONTOLOGY","Score":null,"Total":0}
THE RELATIONSHIP OF THE C-REACTIVE PROTEIN /ALBUMIN RATIO TO IN-HOSPITAL MORTALITY IN ELDERLY PATIENTS WITH NON-ST-ELEVATION MYOCARDIAL INFARCTION WHO HAVE UNDERGONE PERCUTANEOUS CORONARY INTERVENTION
Introduction: Acute myocardial infarction is the most common cardiovascular disease and the cause of significant mortality worldwide. The C-reactive protein/albumin ratio, which measures inflammatory conditions, can be used to predict mortality. In this study, we aimed to investigate the relationship between in-hospital mortality and the C-reactive protein/albumin ratio in patients diagnosed with non-ST-elevation myocardial infarction who underwent interventional treatment at our hospital. Materials and Method: Two hundred and ninety-seven elderly patients were included in the study. The information of the patients was obtained from the hospital database. The C-reactive protein/albumin ratio was calculated for each patient. We used regression analysis to investigate the relationship between the C-reactive protein/albumin ratio and in-hospital mortality. Results: A univariate analysis showed that gender, ejection fraction, white blood cell, glucose, creatinine, systolic and diastolic blood pressure, heart rate, GRACE risk score, and CAR ratio were significant predictors of mortality (Table 2). All parameters were added to a multivariable logistic regression, and multivariable logistic regression analysis showed that the GRACE risk score (OR: 0.956, 95% CI: 0.941–0.971; p<0.001) and the C-reactive protein/albumin ratio (OR: 0.812, 95% CI: 0.661–0.998; p=0.048) were the only significant predictors of mortality. Furthermore, bivariate correlation analysis showed a weak but statistically significant correlation between GRACE risk score and C-reactive protein/albumin ratio (r=0.180, p<0.001). Conclusion: We found a significant relationship between C-reactive protein/albumin and in-hospital mortality. C-reactive protein/albumin ratio can be used in clinical practice because it is inexpensive and easy to apply and has a strong prognostic value for elderly non-ST-elevation myocardial infarction patients. Keywords: Myocardial Infarction; Albumin; Inflammation; Mortality.
期刊介绍:
Turkish Journal of Geriatrics is a peer-reviewed journal. Official language of the journal is English. Turkish Journal of Geriatrics invites submission of Original Articles based on clinical and laboratory studies. Review Articles are published only after the invitation from the Editorial Board.