COVID-19患者住院时间:竞争风险分析的应用

Y. Alimohamadi, M. Sepandi, Anís Dadgar, Homeira Sedighi Nezhad, R. Mosaed, S. Zargar Balaye Jame
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引用次数: 3

摘要

在本研究中,目的是估计德黑兰一家医院入院的COVID-19患者的住院时间。方法:我们使用了2020年3月7日至10月8日在伊朗德黑兰一家转诊医院住院的446例COVID-19住院患者的回顾性数据。使用Kaplan-Meier方法和竞争风险分析分析包括年龄、性别、合并症状态和症状在内的变量的预后影响。住院时间用最后状态时间减去入院时间计算。所有分析均使用SPSS 22.0版和STATA 15版进行。结果:患者平均年龄57.09±16.85岁。所有患者住院时间的中位数(IQR)为7(11-5)天。80岁以上患者住院时间最长,分别为9天(15-5)和7天(11-5)。60 ~ 69岁年龄组94例(21.1%)。其中男性267例(59.9%),女性179例(40.1%)。其中呼吸窘迫249例(55.8例)、咳嗽233例(52.2例)、发热209例(46.9例)最为常见。在合并症中,106例(23.8%)合并心血管疾病,114例(25.6%)合并糖尿病,100例(22.4%)合并高血压。大多数死亡(21例(32.3%))发生在70-79岁年龄组。未充分研究病例的总病死率(CFR)为14.6%。结论:虽然本研究的结果表明,伊朗的住院时间并不比其他国家高,但通过采取一些措施,包括早期发现疑似病例和及时治疗,以及在准备所需设施、药品和设备方面提供必要的资金,可以缩短或至少防止住院时间的增加。
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Hospital length of Stay among COVID-19 Patients: An Application of Competing Risk Analysis
Introduction: In the present study, the goal was to estimate the hospital length of stay among patients admitted with COVID-19 in a hospital in Tehran. Methods: We used retrospective data on 446 hospitalized patients with COVID-19 who admitted from 7 March to 8 Oct 2020 in a referral hospital in Tehran, Iran. The prognostic effects of variables, including age, gender, comorbidity status, and symptoms were analyzed by using Kaplan-Meier methods and a competing risk analysis. Length of stay in hospital was calculated using time of last status minus time of admission. All analyses performed using SPSS version 22.0 and STATA version 15. Results: The mean age of cases was 57.09±16.85 years old. The median (IQR) of hospital length of stay among all patients was 7 (11-5) days. The length of Hospital stay, for >80 years’ patients (9days (15-5)) and females (7days (11-5)) was the longest. The most of cases (94 (21.1%)) were in 60–69 age group. In overall 267 (59.9%) of all cases were males and 179 (40.1%) were females. The most common symptom among patients was Respiratory distress 249 (55.8), Cough 233 (52.2) and fever 209 (46.9) respectively. Regarding having any comorbidities, 106 (23.8%) of COVID-19 cases had Cardiovascular disease, 114 (25.6%) had diabetes and 100 (22.4%) had hypertension. Most of deaths (21 (32.3%)) occurred in 70-79 years’ age group. The overall Case Fatality Rate (CFR) in under-studied cases was 14.6%. Conclusion: Although the result of the present study showed that hospital length of stay in Iran is not higher than in other countries, but by applying some measures including the early detection of suspected cases and timely treatment and necessary funding on preparing required facilities, medicine and equipment, it could be shortened or at least prevented from increasing.
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CiteScore
0.80
自引率
0.00%
发文量
26
审稿时长
12 weeks
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