应用人工神经网络进行肺癌早期检测

IF 0.6 Q4 NUCLEAR SCIENCE & TECHNOLOGY Atom Indonesia Pub Date : 2019-04-30 DOI:10.17146/AIJ.2019.860
Tumpal Pandiangan, Ika Bali, Alexander R. J. Silalahi
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引用次数: 13

摘要

肺癌是一种致命的恶性肺肿瘤,其特点是肺组织中细胞生长不受控制。通常情况下,肺癌的检测是由医生通过x射线图像的目视检查完成的。本研究的目的是创建一种能够从x射线图像中自动检测早期肺癌的计算工具。这项研究有两个主要步骤,第一步是根据x射线图像描述癌症或癌症症状,第二步是开发人工神经网络(ANN)。在第一步中,特别需要制定一个严格的图像处理框架,其顺序步骤是:(i)图像降噪,(ii)图像增强,(iii)肺器官分割,(iv)目标边缘检测,(v)肿瘤边界检测。该框架结合了图像处理技术,如阈值分割和形态检测(侵蚀和膨胀)。该框架有望揭示界定肺癌或早期肺癌的相关特征,如面积、周长、密度剖面和形状比。第二步,基于机器学习算法构建人工神经网络,研究大量确诊肺癌患者的x射线图像。除了单纯基于二维x线图像进行学习外,还结合了之前研究过的肿瘤特征。这两者与大型数据集相结合,有望使机器达到接近100%的检测精度。根据所得到的10个样本的测试结果,人工神经网络的计算值与Matlab程序测量结果的比较值趋于一致。结果表明,人工神经网络已被成功训练,能够正确识别10个样本。
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Early Lung Cancer Detection Using Artificial Neural Network
Lung carcinoma is a malignant lung tumor that is deadly and is characterized by the uncontrolled cell growth in the tissue of lung. Normally the lung cancer detection is done by visual inspection of x-ray image by medical doctor. The purpose of this study is to create a computational tool that can automatically detect early lung cancer from x-ray image. This research has two main steps, with first being to characterize cancer or cancer symptoms based on x-ray images and second step is to develop an artificial neural network (ANN). In first step, particularly it is wanted to lay out a rigorous image processing framework with sequential steps: (i) image noise reduction, (ii) image enhancement, (iii) lung organ segmentation, (iv) object edge detection, and (v) tumor boundary detection. The framework incorporates image processing techniques such as thresholding and morphological detections (erosion and dilation). The framework is expected to reveal the relevant features that define lung cancer or early lung cancer such as area, perimeter, density profile and shape ratio. For the second step, the ANN is built based on machine learning algorithm to study a large set of x-ray images of positively diagnosed lung cancer patients. In addition to learning solely based on the 2D x-ray images, it is also incorporated the previously studied tumor features. The two combined with a large dataset is expected to enable the machine to reach a close to 100 % detection accuracy. Based on the test results of 10 samples obtained the comparative value of the calculated by the ANN with the results of measurement with Matlab program is tends to approach the same. It can be concluded that ANN has been successfully educated so that can identify 10 samples correctly.
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来源期刊
Atom Indonesia
Atom Indonesia NUCLEAR SCIENCE & TECHNOLOGY-
CiteScore
1.00
自引率
0.00%
发文量
20
审稿时长
16 weeks
期刊介绍: The focus of Atom Indonesia is research and development in nuclear science and technology. The scope of this journal covers experimental and analytical research in nuclear science and technology. The topics include nuclear physics, reactor physics, radioactive waste, fuel element, radioisotopes, radiopharmacy, radiation, and neutron scattering, as well as their utilization in agriculture, industry, health, environment, energy, material science and technology, and related fields.
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