Piperine Loaded Titanium Dioxide Nanoparticles: Development,Characterisation and Biomedical Application

TiO 2 nanoparticles were prepared by using electrochemical anodization method. UV-Vis absorption spectrum of TiO 2 and TiO 2 : piperine nanoparticles have an absorption edge in the range of (340 -355) nm, suggesting that the TiO 2 colloidal obtained is anatase phase. The band gap energy (E g ) for TiO 2 nanoparticles (3.46 eV) is higher than the value of (3.20 eV) for bulk TiO 2 . X-Ray diffraction results for TiO 2 nanoparticles with a wavelength of 1.54 Å were investgation in this work. Planes (101), (200), (111), (220), (210), (211), (105), (220), (310), (221), and (220) crystal planes all had peaks with the lattice constants a = 3.755 Å and c = 9.5114 Å confirms the anatase phases of the TiO 2 nanoparticles according to the JCPDS file 21-127231. Scanning Electron Microscope images of TiO 2 samples in revealed the prevalence spherical nanosized crystallites, where clear nanostructures with a grain size of 15 nm. In TEM image, the shape of the nanoparticles was spherecial, with small size variance and found to be 15 nm. The EDX study of the nanoparticle reflects the atomic percentage of elements such as Ti and O with a ratio of 83:17 and no other peaks are observed this confirm the presence of TiO 2 nanoparticles.