津巴布韦穆塔雷高地眼科诊所糖尿病患者糖尿病视网膜病变患病率和危险因素的回顾性研究

Musokeri Tatenda Lewis, W. Mena, Maibouge Tanko Mahamane Salissou
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摘要

目的:了解糖尿病视网膜病变的患病率及其与高血压、年龄、性别和空腹血糖水平的关系。方法:本回顾性研究评估了135例18岁及以上在津巴布韦穆塔雷高地眼科诊所就诊的糖尿病视网膜病变及其相关危险因素的患病率。收集了年龄、性别和视网膜病变类型的数据。根据确定的视网膜病变,将受试者分为无视网膜病变组、非增殖性糖尿病肾病组和增殖性糖尿病视网膜病变组。采用多因素和单因素回归分析,检验视网膜病变的存在与几种危险因素的相关性,结果以百分比表示,以P< 0.05为有统计学意义。结果:研究对象的平均年龄为60.8±14岁,女性占研究对象总数的一半以上(58.5%)。44%的人超重(BMI 25-30), 34.8%的人肥胖,糖尿病视网膜病变的总体患病率为31.1%(非增生性糖尿病肾病,20%;增生性肾病,11.1%)。视网膜病变的比例随着糖尿病持续时间的增加而增加,糖尿病持续时间小于10年者为23.3%,糖尿病持续时间大于10年者为46.6%。单因素分析中,年龄和高血压与糖尿病视网膜病变存在显著相关(P< 0.05),而视网膜病变与空腹血糖无相关性(χ 2检验,P =0.0965)。结论:糖尿病视网膜病变(DR)患病率高(31.1%),非增生性DR多于增生性DR。糖尿病视网膜病变、高血压和年龄之间有很强的相关性。
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Diabetes Retinopathy Prevalence and Risk Factors among Diabetic Patients Seen at Highland Eye Clinic Mutare Zimbabwe: A Retrospective Study
Objective: To determine the prevalence of diabetic retinopathy and its association with hypertension, age, gender, and fasting blood glucose level.Methods: This retrospective study assessed the prevalence of diabetic retinopathy with its associated risk factors on 135 diabetic patients, aged 18 years and above, visiting the Highland Eye Clinic Mutare, Zimbabwe. Data were collected on the age, sex, and type of retinopathy. Based on the identified retinopathy, subjects were divided into no retinopathy, non-proliferative diabetic renopathy, and proliferative diabetic retinopathy groups. Analysis were then performed using multivariate and univariate regression analyses to test the association between the presence of retinopathy and several risk factors, and results were presented in percentages, with P< 0.05  considered to show statistical significance.Results: The average age of the subjects this study was 60.8 ± 14 with female subjects constituted more than half of the total number of subjects (58.5%). Forty four percent were overweight (BMI 25-30), 34.8 % were obese, and the overall prevalence of diabetic retinopathy was 31.1% (non-proliferative diabetic renopathy, 20%; proliferative renopathy, 11.1%). The proportion of subjects with retinopathy increased with duration of DM, being 23.3% in those with a DM duration of less than 10 years and 46.6% in those with a DM duration of more than 10 years. Age and hypertension were significantly associated with the presence of diabetic retinopathy (P< 0.05) in univariate analysis, but no association was identified between retinopathy and fasting blood glucose (chi-square test, P =0.0965)Conclusion: The prevalence of diabetic retinopathy (DR) is high (31.1%), Non-proliferative DR is more common than the proliferative (DR). There is a strong association between diabetic retinopathy, hypertension, and age.
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