跟腱疾病的等距和基于功能的4阶段渐进加载程序:一项为期12个月的初步研究

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2022-05-24 eCollection Date: 2022-01-01 DOI:10.1155/2022/6268590
Thøger Persson Krogh, Thomas Theis Jensen, Merete Nørgaard Madsen, Ulrich Fredberg
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引用次数: 0

摘要

背景跟腱病(AT)是一种常见的肌肉骨骼疾病,其治疗仍然具有挑战性。假设/目的。通过进行一项试点研究,我们旨在评估一项新的基于家庭的4阶段康复计划的可行性、安全性和临床改进,该计划具有渐进负荷,包括在建立随机对照试验之前进行小规模的等长运动。方法。包括10名患有慢性中段AT的娱乐性运动员。主要结果是VISA-A评分在1、2、3、6和12个月后发生变化。次要结果包括触诊肌腱时的压痛和6个月后的超声变化。后果在6个月和12个月的随访中,观察到VISA-A平均改善分别为26.9分(P=0.004)和35.4分(P=0.006)。肌腱触诊时的肌腱(0-10)从5.5降至2.5(P<0.001)。彩色多普勒超声活动(0–4)减少了50%,从平均2级降至1级(P=0.023)。跟腱的低回声截面积从平均29.1%减少到8.5%(P=0.001)。肌腱厚度变化无统计学意义(P=0.415)。结论在基于等长训练和渐进负荷的4阶段AT康复计划之后,我们观察到一组先前未能从标准AT康复中获益的运动员的VISA-A评分和超声检查都有所改善。该研究在高度遵守该计划方面是可行的,并且没有观察到安全问题。这项试点研究的结果支持在未来的随机对照试验中对这种特定的康复方法进行进一步评估。
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An Isometric and Functionally Based 4-Stage Progressive Loading Program in Achilles Tendinopathy: A 12-Month Pilot Study.

Background: Achilles tendinopathy (AT) is a common musculoskeletal disorder, and its management remains challenging. Hypothesis/Purpose. By conducting a pilot study, we aimed to assess the feasibility, safety, and clinical improvement of a new home-based 4-stage rehabilitation program with progressive loading including isometric exercises on a small scale prior to setting up a randomized controlled trial.

Methods: Ten recreational athletes with chronic midportion AT were included. The primary outcome was change in VISA-A score after 1, 2, 3, 6, and 12 months. Secondary outcomes included tenderness on palpation of the tendon and ultrasonographic changes after 6 months.

Results: Average VISA-A improvements of 26.9 points (P=0.004) and 35.4 points (P=0.006) were observed at 6- and 12-month follow-up, respectively. Tenderness on palpation of the tendon (0-10) was reduced from 5.5 to 2.5 (P < 0.001). Color Doppler ultrasound activity (0-4) was reduced by 50%, from an average of grade 2 to grade 1 (P=0.023). The hypoechoic cross-sectional area of the Achilles tendon was reduced from an average of 29.1% to 8.5% (P=0.001). Tendon thickness showed no statistically significant change (P=0.415).

Conclusion: Following the 4-stage rehabilitation program for AT based on isometric training and progressive loading, we observed improvement in both VISA-A score and ultrasonography in a group of athletes who had previously failed to benefit from standard AT rehabilitation. The study was feasible in terms of high adherence to the program and with no observed safety issues. The results of this pilot study support a further assessment of this specific approach for rehabilitation in a future randomized controlled trial.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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