{"title":"长期使用Abemaciclib，一种新的cdk4 /6抑制剂:降低转移性乳腺癌患者肝转移的影响","authors":"O. Zorn, J. Miller, F. Heirler","doi":"10.4172/2324-9110.1000238","DOIUrl":null,"url":null,"abstract":"An 82-year old patient suffering from metastatic breast cancer (FIGO IV D) underwent surgical operations and radiation treatments in the past. From November 29, 2018 until now, the patient was treated with 100 mg Abemaciclib (2 x 50 mg). During therapy, her pain subjectively decreased. No relevant side effects were observed. After 6 months, hepatic metastasis was checked by means of computer tomograph (CT) and a significant reduction of metastasis size was documented.","PeriodicalId":73658,"journal":{"name":"Journal of clinical & experimental oncology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Influence of Long-term Abemaciclib, A New CDK 4/6 Inhibitor: Decrease in Liver Metastasis in a Patient Suffering from Metastatic Breast Cancer\",\"authors\":\"O. Zorn, J. Miller, F. Heirler\",\"doi\":\"10.4172/2324-9110.1000238\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"An 82-year old patient suffering from metastatic breast cancer (FIGO IV D) underwent surgical operations and radiation treatments in the past. From November 29, 2018 until now, the patient was treated with 100 mg Abemaciclib (2 x 50 mg). During therapy, her pain subjectively decreased. No relevant side effects were observed. After 6 months, hepatic metastasis was checked by means of computer tomograph (CT) and a significant reduction of metastasis size was documented.\",\"PeriodicalId\":73658,\"journal\":{\"name\":\"Journal of clinical & experimental oncology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-12-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of clinical & experimental oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4172/2324-9110.1000238\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of clinical & experimental oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2324-9110.1000238","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
一位82岁的转移性乳腺癌患者(FIGO IV D)过去曾接受手术和放射治疗。2018年11月29日至今，患者给予Abemaciclib 100 mg (2 × 50 mg)治疗。治疗期间，她主观上疼痛减轻。未观察到相关副作用。6个月后，通过计算机断层扫描(CT)检查肝转移，发现转移灶明显缩小。
Influence of Long-term Abemaciclib, A New CDK 4/6 Inhibitor: Decrease in Liver Metastasis in a Patient Suffering from Metastatic Breast Cancer
An 82-year old patient suffering from metastatic breast cancer (FIGO IV D) underwent surgical operations and radiation treatments in the past. From November 29, 2018 until now, the patient was treated with 100 mg Abemaciclib (2 x 50 mg). During therapy, her pain subjectively decreased. No relevant side effects were observed. After 6 months, hepatic metastasis was checked by means of computer tomograph (CT) and a significant reduction of metastasis size was documented.
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